ID   U1FYH6_ENDPU            Unreviewed;      1373 AA.
AC   U1FYH6;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EPUS_03524 {ECO:0000313|EMBL:ERF69972.1};
OS   Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Verrucariales; Verrucariaceae; Endocarpon.
OX   NCBI_TaxID=1263415 {ECO:0000313|EMBL:ERF69972.1, ECO:0000313|Proteomes:UP000019373};
RN   [1] {ECO:0000313|Proteomes:UP000019373}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Z07020 / HMAS-L-300199 {ECO:0000313|Proteomes:UP000019373};
RX   PubMed=24438332; DOI=10.1186/1471-2164-15-34;
RA   Wang Y.-Y., Liu B., Zhang X.-Y., Zhou Q.-M., Zhang T., Li H., Yu Y.-F.,
RA   Zhang X.-L., Hao X.-Y., Wang M., Wang L., Wei J.-C.;
RT   "Genome characteristics reveal the impact of lichenization on lichen-
RT   forming fungus Endocarpon pusillum Hedwig (Verrucariales, Ascomycota).";
RL   BMC Genomics 15:34-34(2014).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KE721364; ERF69972.1; -; Genomic_DNA.
DR   RefSeq; XP_007804306.1; XM_007806115.1.
DR   GeneID; 19238564; -.
DR   eggNOG; ENOG502QQWJ; Eukaryota.
DR   HOGENOM; CLU_003023_0_0_1; -.
DR   OMA; VLKSPKW; -.
DR   OrthoDB; 1984726at2759; -.
DR   Proteomes; UP000019373; Unassembled WGS sequence.
DR   CDD; cd04043; C2_Munc13_fungal; 1.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 1.20.58.1100; -; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR010439; MUN_dom.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR014772; Munc13_dom-2.
DR   PANTHER; PTHR47263; ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1; 1.
DR   PANTHER; PTHR47263:SF1; C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350); 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF06292; MUN; 1.
DR   SMART; SM00239; C2; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS51259; MHD2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019373}.
FT   DOMAIN          701..827
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   DOMAIN          907..1023
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          1122..1244
FT                   /note="MHD2"
FT                   /evidence="ECO:0000259|PROSITE:PS51259"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          343..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1373 AA;  156820 MW;  2B49B84486FF637A CRC64;
     MSTSSSQSRG IKGRISSLQN ERKPSLEYSR PRQKHVKLAD AYTFALRVAY LSYLLQPRAR
     RTRQVAVPKP QVHRSSTSFN DLMKDFSLVR DSKSTRFPNG FVPILEKRLT GVLMGKERRK
     EYEDALVKRT FAAFLNAFTD PAFKKRMEKD RRVEDLVLIF FSNATKELQK GKAPGDDSVK
     MMVDRHVALF VRLIGLVMKD QDWTRDRPEL TARLSTLESK LLAHDQDLTQ DQANGALSTV
     EEVVPLSYEV RDMPLVRVVA RIFGFPESMV QSDITKNKPF WTESAALQDL KTYQTHLNLG
     TGRTLNRGDF DTDQAYELWK KSESPDISQL VLAIVQSNPE LAKSAPGGGL PRFNAQPNGM
     PSSDSSYSEA SRRLSLKLED SSSYVIDQSI DMSSLNIGTE GTDWPDDVEN IYTFTPSDPR
     AVYRFILAQA LSFDVKDTSL EASEATSTTP AIKLLSKQST ELLNEIALRW RIPHSSRLVM
     FLDVVRQRYI EQQIDLDTLD TAFIFVKEPP TENKRSSVVM TSVLYEREKW TVTDSVLMQQ
     LLHALEENLL RELYEAIMMS YDAKISPVLG KILYVLDTHI RADPSFVRVP DQEAQFRTTV
     ADGLVNKASE VYGSYVEKEI PQEQEAWEFY HVIQLGKSVI KLAEKIQKRF KKNPEICGVE
     PLAILLECLL PSYAEDARDI IGRILEGAAE KEQEIPIQDG FDLYKELSEV RRIHSNALPD
     VPFPFHVESL LADFVWRWIQ MSSEQINGWV ENAVKQDRFT VRTEGAKAIP TEDERHSISV
     IDIFRSFNQI LDQIFQLNWD DDLGYAKFMT ALSKAIGDGL ARYCDLLDQM FSREMDRLTP
     EQEAAAGQTR QEKWMQLAKD TWNNKERVEP FQFYATSFVK LNDIAFAIRQ WDKLEREINV
     DACMEVIQRH NPPATQKQRK TTNFVFTIKI VEAEDLKACD INGLSDPYVV LTDEYQKRLS
     KTRVIMHSLN PRWDDTVDIV TRSPLNIIAT IWDWDNFGDH DYVGRTSIKL DPAHFSDFMP
     REYWLDLDTQ GRLLLRVSME GERDDIQFYF GRTFRTLKRT ERDMTRKITD KLSAYINHCL
     SRRALRSLLS RGISISSVSS YFKGNRQSTA LASSGPTEAD ISNAVKPLFT YFDDNFAIMN
     LTLTSEAMIM VMTRLWKEVL VTIESILVPP LSDKPSQQRP LTQQELDVVF KWLQLLFDFF
     HAVDEETGEA NGVPTNVLKS PKYHEIQTLN FFYFDTTENL IRTSERMASA TAARQAANRN
     RLSAPPSLGM SFGSGPAGLM GMPSTRRAKS IMLSRNLGTM RKAKEEKWKE AQADPNDDMI
     LRILRMRPEA ANYLRDRSRQ KERLAAAAAA DLIVRQSLLA GSGGRMAGTL GRR
//