ID U1PAR8_9EURY Unreviewed; 545 AA.
AC U1PAR8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=J07HX5_01345 {ECO:0000313|EMBL:ERG89191.1};
OS halophilic archaeon J07HX5.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales.
OX NCBI_TaxID=1325472 {ECO:0000313|EMBL:ERG89191.1};
RN [1] {ECO:0000313|EMBL:ERG89191.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23637883;
RA Podell S., Ugalde J.A., Narasingarao P., Banfield J.F., Heidelberg K.B.,
RA Allen E.E.;
RT "Assembly-driven community genomics of a hypersaline microbial ecosystem.";
RL PLoS ONE 8:E61692-E61692(2013).
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010}.
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DR EMBL; KE356559; ERG89191.1; -; Genomic_DNA.
DR HOGENOM; CLU_499335_0_0_2; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01445; intein_Nterm; 1.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF14890; Intein_splicing; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR SMART; SM00306; HintN; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein splicing {ECO:0000256|ARBA:ARBA00023000}.
FT DOMAIN 274..330
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 545 AA; 61163 MW; 3B25A6CCE3775997 CRC64;
MAAADDPELV ETFEEFYRSY YRNEIGELAR KYPSEQKSLY VDWQELYQFD PDLADDLRRK
PGQLIDYAEE ALRLYDLPVD VSLGQAHVRV QRLSETTDIR AIRADHRGTL LQVQGVVRKA
TEVRPKITTA AFECQRCGTL TRIPQDGDFQ EPHECSGCER QGPFRVNYDQ SEFVDAQQLR
VQESPEGLRG GETPQSIDIT IEDDITGGVT AGDSVTATGI LRLDQRGGER DKSAVFDTYM
EGYAVEIDDQ QFEEMTITDE DKQQIIELSN DPNVYDQIEG AIAPSIYGYE TEKRAMAFQL
FSGVTKHLPD GSRTRGDLHI LLIGDPGTGK CLAGDQRVTL SDGREQPIRE LVETHLDEPT
PVDDGVYDTA DIQLPSLTAD GQIEHRRATK VWKREAPAEM YRITTAGGQT LEMTPSHPLF
VQSDGGLVHR PARDLTEGTF VAAPDTARSG TTRDVVPVTG KXXXXXXXLT AERDPPRDIA
GVGERCLDQC RTVGVWFSSK PFVTLETVQF FRIRAGVSPQ VLFHRLQTTD IMREREHVIG
CRRRN
//
