ID   U2D697_9FIRM            Unreviewed;       224 AA.
AC   U2D697;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=TVP38/TMEM64 family membrane protein {ECO:0000256|RuleBase:RU366058};
GN   ORFNames=HMPREF1982_02490 {ECO:0000313|EMBL:ERI92295.1};
OS   Clostridiales bacterium oral taxon 876 str. F0540.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales.
OX   NCBI_TaxID=1321778 {ECO:0000313|EMBL:ERI92295.1, ECO:0000313|Proteomes:UP000016490};
RN   [1] {ECO:0000313|EMBL:ERI92295.1, ECO:0000313|Proteomes:UP000016490}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0540 {ECO:0000313|EMBL:ERI92295.1,
RC   ECO:0000313|Proteomes:UP000016490};
RA   Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA   O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA   Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU366058};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU366058}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC       {ECO:0000256|RuleBase:RU366058}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERI92295.1}.
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DR   EMBL; AWSZ01000053; ERI92295.1; -; Genomic_DNA.
DR   AlphaFoldDB; U2D697; -.
DR   STRING; 1321778.HMPREF1982_02490; -.
DR   PATRIC; fig|1321778.3.peg.2458; -.
DR   eggNOG; COG0398; Bacteria.
DR   HOGENOM; CLU_038944_12_0_9; -.
DR   Proteomes; UP000016490; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR015414; TMEM64.
DR   InterPro; IPR032816; VTT_dom.
DR   PANTHER; PTHR12677:SF49; TVP38_TMEM64 FAMILY MEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU366058};
KW   Membrane {ECO:0000256|RuleBase:RU366058};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016490};
KW   Transmembrane {ECO:0000256|RuleBase:RU366058};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU366058}.
FT   TRANSMEM        20..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   TRANSMEM        57..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   TRANSMEM        90..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   TRANSMEM        138..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   TRANSMEM        164..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   TRANSMEM        197..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   DOMAIN          71..187
FT                   /note="VTT"
FT                   /evidence="ECO:0000259|Pfam:PF09335"
SQ   SEQUENCE   224 AA;  24816 MW;  824508FCB56C0257 CRC64;
     MKLISYKEVL SVKKISRFSI IAVWAGLIYI LYRMNLLTGN MDNLNQFFDS CGKYKPLVFI
     ALSSLRIAAL IPSAVFMILG GMMFSPIQGF ALTLISVILS ETIVYIASKV LVSSGIKDYI
     VNKNPKLYEL LIRNNTKILA IGILCPIAPS DAVCFLGSST GLNYVKFMLT VLAANMPMMI
     LYSFLGNSVI YSVNNTIIIS GIIIAVSTYS IYLWNKAQRS HRLV
//