ID U2MYT9_9CLOT Unreviewed; 783 AA.
AC U2MYT9;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:ERK28412.1};
GN ORFNames=CINTURNW_4285 {ECO:0000313|EMBL:ERK28412.1};
OS Clostridium intestinale URNW.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1294142 {ECO:0000313|EMBL:ERK28412.1, ECO:0000313|Proteomes:UP000016721};
RN [1] {ECO:0000313|EMBL:ERK28412.1, ECO:0000313|Proteomes:UP000016721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=URNW {ECO:0000313|EMBL:ERK28412.1,
RC ECO:0000313|Proteomes:UP000016721};
RX PubMed=24136853;
RA Lal S., Ramachandran U., Zhang X., Sparling R., Levin D.B.;
RT "Draft Genome Sequence of the Hydrogen- and Ethanol-Producing Bacterium
RT Clostridium intestinale Strain URNW.";
RL Genome Announc. 1:e00871-13(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK28412.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; APJA01000035; ERK28412.1; -; Genomic_DNA.
DR RefSeq; WP_021804133.1; NZ_KI273145.1.
DR AlphaFoldDB; U2MYT9; -.
DR STRING; 1294142.CINTURNW_4285; -.
DR PATRIC; fig|1294142.3.peg.4421; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_53_9; -.
DR OrthoDB; 9762141at2; -.
DR Proteomes; UP000016721; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR007892; CHASE4.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF05228; CHASE4; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016721};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 308..361
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 397..531
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 535..783
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 783 AA; 89326 MW; 55F71698D74DBE13 CRC64;
MIKHDKIKKS KKYQLRSQIS IFFLLTIVAS VLIVYGLSNR FIIRNFDYLL KNQGQGNMKQ
VVNELNNQLI DLENSAKDYG SWDDTYNYVL NRDKSYIDSN YIDETFSLNN WNLLYIFDKD
KELAYGKEFD LHNKQEINKS DEIIDFIKGK EWIFNDIRIQ AKLISSPKGS MLLAAYPITR
SGGLGNSVGW IVCGKYVNEN LVNSMGDNLL MNLKLDDNID KPGDITSTTY ISGRGIKADI
WVDKNGKSDK SVGIIYDYDG NKLIKMSSNI DVDLNILNMG TYGVYKYIAT TSVVLLVSFI
LLLWLIDKTI FKRLNELIYN VGNIEKNNDF SKRISIERND EISILETGFN NLLSTVERTQ
SEILYQAKYD QLTETFNRGV FFDDVQVILD DEMKKGNKSA IIFIDIDGFK DINDSLGHST
GDYILVNVAS RLKEKLKNYN PIISRFGGDE FVTFIPNIKS YKEIDNLCKD LLDRIKQPMY
IGRKACKITC SIGISISIDH GSTVDDLINN ADVAMYHVKK NNKNSSIIYN EDMRSRISQE
MLEEALDNKE FVLYYQKQVD ITTERIEGAE ALVRWNSADR GFVSPIEFIP LAEETGFIVP
LGKWILEEAC KQCKEWNDTI DKDFRVSVNV SSIQFMEKAF ISMVVSTLKT TGINPKNLEL
EITESVALYK EEEVISKLEE LKNLGVRVSI DDFGTGYSSL KYLQKFKIDG LKIDKAFIDN
INENSSIAKS IISMAENLGV YVIAEGVETV EQVNCLRSLK CQYIQGYYYG KPVPPDGFDL
KIS
//
