ID U2QKY1_9ACTN Unreviewed; 561 AA.
AC U2QKY1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Ribulokinase {ECO:0000256|RuleBase:RU003455};
DE EC=2.7.1.16 {ECO:0000256|RuleBase:RU003455};
GN Name=araB {ECO:0000313|EMBL:ERK63545.1};
GN ORFNames=HMPREF0682_1099 {ECO:0000313|EMBL:ERK63545.1};
OS Propionibacterium acidifaciens F0233.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Propionibacterium.
OX NCBI_TaxID=553198 {ECO:0000313|EMBL:ERK63545.1, ECO:0000313|Proteomes:UP000017052};
RN [1] {ECO:0000313|EMBL:ERK63545.1, ECO:0000313|Proteomes:UP000017052}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0233 {ECO:0000313|EMBL:ERK63545.1,
RC ECO:0000313|Proteomes:UP000017052};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-ribulose = ADP + H(+) + L-ribulose 5-phosphate;
CC Xref=Rhea:RHEA:22072, ChEBI:CHEBI:15378, ChEBI:CHEBI:16880,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58226, ChEBI:CHEBI:456216;
CC EC=2.7.1.16; Evidence={ECO:0000256|RuleBase:RU003455};
CC -!- PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-
CC ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route):
CC step 2/3. {ECO:0000256|RuleBase:RU003455}.
CC -!- SIMILARITY: Belongs to the ribulokinase family.
CC {ECO:0000256|RuleBase:RU003455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK63545.1}.
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DR EMBL; ACVN02000009; ERK63545.1; -; Genomic_DNA.
DR RefSeq; WP_021796109.1; NZ_ACVN02000009.1.
DR AlphaFoldDB; U2QKY1; -.
DR OrthoDB; 9805576at2; -.
DR UniPathway; UPA00145; UER00566.
DR Proteomes; UP000017052; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0008741; F:ribulokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019569; P:L-arabinose catabolic process to xylulose 5-phosphate; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005929; Ribulokinase.
DR NCBIfam; TIGR01234; L-ribulokinase; 1.
DR PANTHER; PTHR43435:SF4; FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43435; RIBULOKINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Arabinose catabolism {ECO:0000256|ARBA:ARBA00022935,
KW ECO:0000256|RuleBase:RU003455};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|RuleBase:RU003455};
KW Kinase {ECO:0000256|RuleBase:RU003455, ECO:0000313|EMBL:ERK63545.1};
KW Transferase {ECO:0000256|RuleBase:RU003455, ECO:0000313|EMBL:ERK63545.1}.
FT DOMAIN 6..277
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 291..488
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 561 AA; 60060 MW; E348C7179D121D2E CRC64;
MSSGTYVLGI DFGTLSGRAV VVDAATGEQL GTHVTEYPHG VMDTALTAGD GRSLPPEFAL
QDPRDYVEVL RRSVPAAVGT AGVEASDIVG IGIDATSATV LLTDRHGTPL CEKPGFENDI
HAYVKLWKHH GAQNQATRLV KIAEARREPW LARYGGVLSS ELLLPKVLEV FEMAPQTYAA
ADVVVDLVDW LTWRLTGTLT AAAGDSGYKR MLQDGSYPSR EYLEAVRPGF GSVYEDRMDY
PVIPLGGRVG GLTAEFAELM GLPEGISVAA GNIDAHVVVA GANAVRPGQL TAILGTSSCY
VLNDRQYHDC PGVFGIVDGG AVDGSWGFEA GQTAVGDIFA WFVDHCVPAE YEREAAARGL
SAHELLVEKA SGQEIGEHGL VALDWHNGNR SILADARLSG LVLGQTLATR PEDVYRALLE
ATAFGCRVII ENFEEHGIGV DEIVAAGGLL RNTTYMQLLA DITRRPISLS LAEQTGALGA
AVFAAVAAGV HPDVFVAADA MASVERNAYV PRETVSEQYD ALYDIYKELH DLFGRYNGVS
PMHRLKEIRA RIFRDRAPAG A
//
