ID   U2TCC1_9ACTN            Unreviewed;       798 AA.
AC   U2TCC1;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Glycoside hydrolase, family 39 {ECO:0000313|EMBL:ERL10699.1};
GN   ORFNames=HMPREF1316_1135 {ECO:0000313|EMBL:ERL10699.1};
OS   Olsenella profusa F0195.
OC   Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales; Atopobiaceae;
OC   Olsenella.
OX   NCBI_TaxID=1125712 {ECO:0000313|EMBL:ERL10699.1, ECO:0000313|Proteomes:UP000016638};
RN   [1] {ECO:0000313|EMBL:ERL10699.1, ECO:0000313|Proteomes:UP000016638}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0195 {ECO:0000313|EMBL:ERL10699.1,
RC   ECO:0000313|Proteomes:UP000016638};
RA   Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA   Methe B., Sutton G., Nelson K.E.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 39 family.
CC       {ECO:0000256|ARBA:ARBA00008875}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERL10699.1}.
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DR   EMBL; AWEZ01000006; ERL10699.1; -; Genomic_DNA.
DR   RefSeq; WP_021725023.1; NZ_AWEZ01000006.1.
DR   AlphaFoldDB; U2TCC1; -.
DR   STRING; 1125712.HMPREF1316_1135; -.
DR   PATRIC; fig|1125712.3.peg.188; -.
DR   eggNOG; COG2207; Bacteria.
DR   eggNOG; COG3664; Bacteria.
DR   OrthoDB; 9799345at2; -.
DR   Proteomes; UP000016638; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR   InterPro; IPR049166; GH39_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR037923; HTH-like.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   PANTHER; PTHR43280; ARAC-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR43280:SF6; RCS-SPECIFIC HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RCLR; 1.
DR   Pfam; PF01229; Glyco_hydro_39; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 2.
DR   SUPFAM; SSF51215; Regulatory protein AraC; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ERL10699.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016638}.
FT   DOMAIN          163..261
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000259|PROSITE:PS01124"
FT   REGION          258..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   798 AA;  91653 MW;  CE36B555EF364568 CRC64;
     MFLQNLDFSI VRAKTGVSYA QTNLFVFFVL EGRMTVRYRE EDISLAKDDV LLVAPGMGCM
     IRKSQDALYG VASFPMELIH AVIGSQHIVL YANSVRDASH AYADLREVFN DLIAEYTSDT
     NRTHALRDSL LLKLLNTLIE NYQLSFANVG EVGDDASNDA RMEEAIRYVL NNLTTNITLS
     RLARSMYISP STLSRLFKHG TGINFTEYVS RLRVQMSLEL LESSDKNLTE IALACGFSSP
     VTFNRAFHKV MGTSPSGFRK TNRQNAKQLK QQRQKDEREV RRELVEKGYR APQSRHQEDL
     LLDIERTHIE RHACLGIINM GNIADIMQIQ QHVLHLHKNL HFRYFRIWNI FSRSLKVSDG
     MTFGSYNFYE LDTVLDFFVT NNLKPYICLG RRPNMALKSL GNNVFYMDDC VQFVSKRIWA
     DCLSSLLDEM VNRYGLTEVS TWIFEFDRDY DHDDSMESYA GDPFDFFDAW KTAYRIVHEK
     VPGALFGGIS GEVVENYSFL KRFYQRCIAE HCAPDFASFL LFPYFSGSGD KQRRRICPDV
     SFVKLLVEKM RSLMDESGMG GRRLFISEFN SSISNRNYLN DSCMRAAWTI EAIRHVDTQV
     DCVCLMAGSD WISNYSDASC IIEGKIGLLS QDGIRKPVYF AIDFLNQLGE RLIAQGDNYV
     ATLQDNGDIY ILCFYYAYPQ AIRNLTNENI GLNECISYHA VGALPLTLNF AIEHLCLPGE
     YCVKKRVIDT SHGDVVGEWR KFQFERHLTT RDVDYLRAVC CPCISIDRKT VDSRKRLWVQ
     TTLKPNSIVS LHIYRHKK
//