ID U2UU47_STRPY Unreviewed; 479 AA.
AC U2UU47;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Oligoendopeptidase F {ECO:0000313|EMBL:ERL21735.1};
DE EC=3.4.24.- {ECO:0000313|EMBL:ERL21735.1};
GN Name=pepF_2 {ECO:0000313|EMBL:ERL21735.1};
GN ORFNames=HMPREF1231_0450 {ECO:0000313|EMBL:ERL21735.1};
OS Streptococcus pyogenes GA06023.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1115816 {ECO:0000313|EMBL:ERL21735.1, ECO:0000313|Proteomes:UP000016663};
RN [1] {ECO:0000313|EMBL:ERL21735.1, ECO:0000313|Proteomes:UP000016663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GA06023 {ECO:0000313|EMBL:ERL21735.1,
RC ECO:0000313|Proteomes:UP000016663};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL21735.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWPJ01000098; ERL21735.1; -; Genomic_DNA.
DR AlphaFoldDB; U2UU47; -.
DR PATRIC; fig|1115816.3.peg.446; -.
DR Proteomes; UP000016663; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1370.20; Oligoendopeptidase f, C-terminal domain; 1.
DR InterPro; IPR013647; OligopepF_N_dom.
DR InterPro; IPR042088; OligoPept_F_C.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR InterPro; IPR004438; Peptidase_M3B.
DR NCBIfam; TIGR00181; pepF; 1.
DR PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11804:SF45; SIMILAR TO OLIGOENDOPEPTIDASE; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR Pfam; PF08439; Peptidase_M3_N; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ERL21735.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 20..56
FT /note="Oligopeptidase F N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08439"
FT DOMAIN 79..459
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
SQ SEQUENCE 479 AA; 54990 MW; E6801F3D8E8EE45A CRC64;
MLDTLEKNPY FSAAIRMAKI QKEHLLSPDV EKALANLREV INAPYDIYTK MRASDFDMDD
FEVDGKTYKN SFVSYENFYQ NHENAEIREK AFRSFSNGLR KHQNTAAAAY LAKVKSEKLL
ADMKGYASVF DYLLAEQEVD RSLFDRQIDL IMTEFGPVAQ KFLKHVAQVN GLEKMTFADW
KLDIDNDLNP EVSIDGAYDL VMKSLAPLGQ EYTKEIERYQ TERWVDFAAN ANKDSGGYAA
DPYKVHPYVL MSWTGRMSDV YTLIHEIGHS GQFIFSDNHQ SYFNTHMSTY YVEAPSTFNE
LMLSDYLEHQ FDDPRQKRFA LAHRLTDTYF HNFITHLLEA AFQRKVYTLI EEGGTFGADQ
LNAMMKEVLT DFWGDAVDID DDAALTWMRQ AHYYMGLYSY TYSAGLVMST AGYLNLKNNP
DGAKEWLDFL KSGGSRTPLD TAMLIGADIA TEKPLRDTIQ FLSDTVDQII NYTEEMSHA
//
