ID U2W6E8_9FIRM Unreviewed; 301 AA.
AC U2W6E8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative citrate (Pro-3S)-lyase, beta subunit {ECO:0000313|EMBL:ERL23087.1};
GN ORFNames=HMPREF1986_00060 {ECO:0000313|EMBL:ERL23087.1};
OS Oribacterium sp. oral taxon 078 str. F0263.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Oribacterium.
OX NCBI_TaxID=1321782 {ECO:0000313|EMBL:ERL23087.1, ECO:0000313|Proteomes:UP000016659};
RN [1] {ECO:0000313|EMBL:ERL23087.1, ECO:0000313|Proteomes:UP000016659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0263 {ECO:0000313|EMBL:ERL23087.1,
RC ECO:0000313|Proteomes:UP000016659};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL23087.1}.
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DR EMBL; AWVU01000004; ERL23087.1; -; Genomic_DNA.
DR AlphaFoldDB; U2W6E8; -.
DR PATRIC; fig|1321782.3.peg.55; -.
DR eggNOG; COG2301; Bacteria.
DR HOGENOM; CLU_044864_0_0_9; -.
DR Proteomes; UP000016659; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR InterPro; IPR011206; Citrate_lyase_beta/mcl1/mcl2.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR32308:SF10; CITRATE LYASE SUBUNIT BETA; 1.
DR PANTHER; PTHR32308; LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED; 1.
DR Pfam; PF03328; HpcH_HpaI; 1.
DR PIRSF; PIRSF015582; Cit_lyase_B; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:ERL23087.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|PIRSR:PIRSR015582-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR015582-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000016659}.
FT DOMAIN 12..231
FT /note="HpcH/HpaI aldolase/citrate lyase"
FT /evidence="ECO:0000259|Pfam:PF03328"
FT BINDING 73
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR015582-1"
FT BINDING 136
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR015582-2"
FT BINDING 136
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR015582-1"
FT BINDING 163
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR015582-2"
SQ SEQUENCE 301 AA; 33476 MW; 95944C4337EABB3A CRC64;
MIENPNKKRL RRSMMFLNAQ KPSLIKDPYI YGADSLMLDL EDAVAATAKD TARFSLYHAL
RSIDYRGSER VVRINGLDTD LWEEDIRCVV AGGADVIRIP KTENADMVRA VEDKVLAAEE
EFHREPGTTL LMSALESAKG VMNAYEICTA SDRMIGVALS GGDYTKDLQT RITGTGVELM
GARQQMIIAA RAAGVQCFDT VWTNLDDMEG FRKDVETIHM MGFDGKSCIN PRQIDVVHKI
FTPTMKEILF SEKVIREIDD KKAKGIGVFT VDGKMIDIAF YDGAKRNIML AKAAGIYKGD
L
//
