ID U3C8V2_CALJA Unreviewed; 1909 AA.
AC U3C8V2; F7EQE5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Plexin-B3 isoform 1 {ECO:0000313|EMBL:JAB15307.1};
GN Name=PLXNB3 {ECO:0000313|EMBL:JAB15307.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB15307.1};
RN [1] {ECO:0000313|EMBL:JAB15307.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB04616.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB48472.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB25577.1}, and Hippocampus
RC {ECO:0000313|EMBL:JAB15307.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; GAMT01007245; JAB04616.1; -; mRNA.
DR EMBL; GAMS01007829; JAB15307.1; -; mRNA.
DR EMBL; GAMR01008355; JAB25577.1; -; mRNA.
DR EMBL; GAMP01004283; JAB48472.1; -; mRNA.
DR RefSeq; XP_002763452.2; XM_002763406.3.
DR OrthoDB; 1387371at2759; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd01179; IPT_plexin_repeat2; 1.
DR CDD; cd12791; RasGAP_plexin_B3; 1.
DR CDD; cd11277; Sema_plexin_B3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR041362; TIG2_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF33; PLEXIN-B3; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF01833; TIG; 3.
DR Pfam; PF18020; TIG_2; 1.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 3.
DR SMART; SM00423; PSI; 3.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..44
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 45..1909
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015101318"
FT DOMAIN 31..471
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 1909 AA; 207159 MW; B08348845DD0A80A CRC64;
MCRTVQETPL LLHFTAPVMV RWPPFSLCLL LLLLSPPPLP LTGAHRFSAP NTTLNHLALA
AGRGTLYVGA VNRLFQLSPE LQLEAMAVTG PVIDSPDCVP FRDPAECPQA QLTDNANQLL
LVSSRTQELV ACGQVRQGVC ETRRLGDVAE VLYQAEDPGD GQFVAANTPG VATVGLVVPS
PTQDLLLVAR GLAGKLSAGV PPLAVRQLAG PQPFSSEGLG RLVVGDFSDY NNSYVGAFAD
NRSAYFVFRR RGARAQAEYR SYVARVCLGD ANLYSYVEVP LACQGQGLIQ AAFLAPDTLL
GAFAAGPRGT QAALCAFPMV ELGASMEQAR RLCYTAGGRG PSGAEEATVE YGVTSRCVTL
PLDSPESYPC GDEHTPSPIA GRQALEAQPL LQLTQSVSAV AALQADGHMI AFLGDTQGQL
HKVFLHGSQG QVYHSQQVGP LGSAISPDLL LDSSGSYLYV LTAHQVDQIP VAACPQFPDC
ASCLQAQDPL CGWCVLQGRC TRKGQCRRAG QPNQWLWSYE ENSHCPHIQS LLPGHHPRQE
QGQVTLSVPR LPTLAADEYF HCAFGDYDSL AYVEGPHVAC VTPPQDQVPL SPPGTDHVTV
PLALVFEDVA VAATNFSFYD CSAVQALEGA APCRACVGSI WRCHWCPQSS HCVYGEHCPE
GERTIYSAQE VDVQARGPGA CPQVEGLAGP HLVPVGWESH LALLVRNLQH FRGLPASFHC
WLELPGELRG LPAILEETAG DSGLIHCQAH QFHPSMSQRE LPVPIYVTQG KAKRLDNAHA
LYVILYDCAM GHPDCSHCQA ANGSLGCVWC ADGQPACRYG PLCPPGAVEL LCPAPSIDAV
EPLTGPPEGG LALTILGSNL GRTFTDVQYA VSVASRPCNP EPSLYRTSAR IVCVTSPAPN
GTTGPVQVAI KSQPPGISSQ HFTYQDPVLL SLSPRWGPQA GGTQLTIHGQ HLQTGSTSSA
FVGGQPCPIL EPVCPEAIVC RTRPQAVPGE AAVLVVFGHV QRTLLTSPFR YTANPQLIAA
EPSASFRGGG RLIRVRGTGL DAAQRPLLSV WLEADGMVQA SRIQPRDPEP RRSCGAPAAD
PQACIQLGGG LLQCSTVCSV NSSSLLLCWS PAVPDGARLR RVFFTLDNVQ VDFASASGGQ
GFLYQPNPRL APLSHEGPTR PYRLKPGHIL DVEGEGLNLG ISKEEVRVYI GRGECLVKTL
TRTHLYCEPP VRAPQPANGS VLPQFVVHMG NLQLALGPVQ YEAEPPLSAF PVEAQAGLGM
GAAVLIAAVL LLTLMYRHKS KQALRDYQKV LLQLESLETG VGDQCRKEFT DLMTEMTDLS
SDLEASGIPF LDYHTYAERA FFPGHGSYPL QPQPEGLGED GRCATVRQGL TQLSNLLNSK
LFLLTLIHTL EEQPTFTQRD RCHVASLLSL ALHGKLEYLT DIMRTLLGDL AAHYVHRNPK
LMLRRTETMV EKLLTNWLSI CLYTFLREVA GEPLYMLFRA IQYQVDKGPV DAVTGKAKRT
LNDSRLLRED VEFQPLTLMV LVGPEAGGAA GSSEVQRVPA RVLDTDTITQ VKEKVLDQVY
KGTPFSQRPS VHALDLEWRS GLAGHLTLSD EDLTSVTHNH WKRLNTLQHY KVPDGATVGL
VPQLHSGGAV CQSLAQSCPL GENISMLEDG EEGGVHLWHL VKATEEPEEA KVRRSSLRER
ELAQAKAIPE IYLTRLLSMK GTLQKFVDDT FQAILSVNRP VPIAVKYLFD LLDELAEKHG
IEDPGTLHIW KTNSLLLRFW VNALKNPQLI FDVRVSDNVD AILAVIAQTF IDSCTTSEHK
VGRDSPVNKL LYAREIPRYK QMVERYYADI HQSSPASYQE MNSALAELSR NYTSAPHCLE
ALQELYNHIH RCYDQIISAL EEDPVGQKLQ LACRLQQVAA LVENKVTDL
//
