ID U3CME3_CALJA Unreviewed; 723 AA.
AC U3CME3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=nucleoside-diphosphate kinase {ECO:0000256|ARBA:ARBA00012966};
DE EC=2.7.4.6 {ECO:0000256|ARBA:ARBA00012966};
GN Name=AK7 {ECO:0000313|EMBL:JAB20332.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB20332.1};
RN [1] {ECO:0000313|EMBL:JAB20332.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Hippocampus {ECO:0000313|EMBL:JAB20332.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
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DR EMBL; GAMS01002804; JAB20332.1; -; mRNA.
DR AlphaFoldDB; U3CME3; -.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0009123; P:nucleoside monophosphate metabolic process; IEA:UniProt.
DR GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 1.
DR CDD; cd22967; DD_AK7; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR047499; DD_AK7.
DR InterPro; IPR007858; Dpy-30_motif.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23359:SF105; ADENYLATE KINASE 7; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 1.
DR Pfam; PF05186; Dpy-30; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:JAB20332.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 417..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 616..675
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 420..436
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 723 AA; 82595 MW; E2094B0A73D0D6E1 CRC64;
MAEEEESAAP SEKVLRIQRV FVNLLDSYSS GNIGKFLSNC VVGASLEEIT EEEEEEDEIK
SVMWEASATK VKEGTFQVVG TLSKPESPQP DFAVETYSAI SREDLLLRLL ECDVIIYNIT
ESPQQVEEAI WAVSALNEEV SHFEKQKVFI LLSTVLTWAR SKALDPEDSE VPFTEEDYRR
RKAHPNFLDH INAEKMVLKY GKKSRKFSTY VVAAGLQYGA EGGILHTFFK MAWLGEIPAL
PVFGDGTNVI PAIHVLDLAG VIQNVIDHAP KPRYLVAVDE SVHTLEDLVK CISKNAGPGK
IQKIPRENAY LMKDLTQDRL DHLLVNLRME ALFVKENFNI RWAAQTGFVE NINSILKEYK
QSRGLMPIKI CILGPPAVGK SSIAEELSKY YKLHHIQLKD VISEAIAKLE AIVAPKDVGE
GEEEGEEEEE QENVEDAQEL LDGIRESMEQ NAGKLDDQYI IRFMKEKLKS MPCRNQGYIL
DGFPETYDQA KDLFSQEDEE EEDEVRGRMF PFDKVIIPEF VCALDASDEF LKERVINLPE
SIVAGTHYSQ DRFLRALSNY RDINLEDETV LNYFDEIEIH PIHIDVGKLE DAQNRLAIKQ
LIKEIGEPQN YGLTDEEKAE KEWKAAEERL AREAAEKAER EHKEAVETAE KIARWEEWNK
RLEEVKREER ELLEAQSVPL RNYLMTYVMP TLIQGLNECC NVRPEDPVDY LAEYLFKNNP
EAQ
//
