ID U3CWQ5_CALJA Unreviewed; 212 AA.
AC U3CWQ5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=dTMP kinase {ECO:0000256|ARBA:ARBA00012980};
DE EC=2.7.4.9 {ECO:0000256|ARBA:ARBA00012980};
GN Name=DTYMK {ECO:0000313|EMBL:JAB02425.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB02425.1};
RN [1] {ECO:0000313|EMBL:JAB02425.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB02425.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB23991.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB18550.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB41436.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- PATHWAY: Pyrimidine metabolism; dTTP biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004992}.
CC -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC {ECO:0000256|ARBA:ARBA00009776}.
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DR EMBL; GAMT01009436; JAB02425.1; -; mRNA.
DR EMBL; GAMS01004586; JAB18550.1; -; mRNA.
DR EMBL; GAMR01009941; JAB23991.1; -; mRNA.
DR EMBL; GAMQ01000415; JAB41436.1; -; mRNA.
DR AlphaFoldDB; U3CWQ5; -.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004798; F:thymidylate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01672; TMPK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00165; Thymidylate_kinase; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039430; Thymidylate_kin-like_dom.
DR InterPro; IPR018095; Thymidylate_kin_CS.
DR InterPro; IPR018094; Thymidylate_kinase.
DR NCBIfam; TIGR00041; DTMP_kinase; 1.
DR PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR PANTHER; PTHR10344:SF1; THYMIDYLATE KINASE; 1.
DR Pfam; PF02223; Thymidylate_kin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS01331; THYMIDYLATE_KINASE; 1.
PE 2: Evidence at transcript level;
KW Kinase {ECO:0000313|EMBL:JAB02425.1};
KW Transferase {ECO:0000313|EMBL:JAB02425.1}.
FT DOMAIN 11..191
FT /note="Thymidylate kinase-like"
FT /evidence="ECO:0000259|Pfam:PF02223"
SQ SEQUENCE 212 AA; 23897 MW; 5AF4A0ECCA9D3C08 CRC64;
MAARRGALIV LEGMDRAGKS TQSRKLVDAL CALGHRAELL RFPERSTEIG KLLSSYLEKK
SDLEDHSVHL LFSANRWEQV PLIKEKLSQG VTLVMDRYAF SGVAFSGAKE NFSLDWCKQP
DVGLPRPDLV LFLQLQLADA AKRSAFGHER YENGAFQERA LQCFHQLMRD TTVNWKMVDA
SKSIEAVHED ILVLAEDAIR TATEKPLGEL WK
//
