ID U3DQW5_CALJA Unreviewed; 416 AA.
AC U3DQW5; F7DY72;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=ADP ribosylation factor GTPase activating protein 1 {ECO:0000313|Ensembl:ENSCJAP00000018558.3};
DE SubName: Full=ADP-ribosylation factor GTPase-activating protein 1 isoform b {ECO:0000313|EMBL:JAB12160.1};
GN Name=ARFGAP1 {ECO:0000313|EMBL:JAB12160.1,
GN ECO:0000313|Ensembl:ENSCJAP00000018558.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB12160.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000018558.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB12160.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Cerebral cortex {ECO:0000313|EMBL:JAB24049.1}, and Hippocampus
RC {ECO:0000313|EMBL:JAB12160.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000018558.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; GAMS01010976; JAB12160.1; -; mRNA.
DR EMBL; GAMR01009883; JAB24049.1; -; mRNA.
DR Ensembl; ENSCJAT00000019607.4; ENSCJAP00000018558.3; ENSCJAG00000010078.5.
DR GeneTree; ENSGT00890000139515; -.
DR OrthoDB; 389572at2759; -.
DR Proteomes; UP000008225; Chromosome 5.
DR Bgee; ENSCJAG00000010078; Expressed in frontal cortex and 6 other cell types or tissues.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08830; ArfGap_ArfGap1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46395; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR46395:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 7..124
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 128..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 45801 MW; AA9D1AAD4F02173F CRC64;
MASPRTRKVL KEIRVQDENN VCFECGAFNP QWVSVTYGIW ICLECSGRHR GLGVHLSFVR
SVTMDKWKDL ELEKMKVGGN AKFREFLESQ EDYDPCWSLQ DKYNSRAAAL FRDKVTALAE
GREWSLESSP AQNWTPPQPR TLPSTVHRAS GQPQNVIASS DKAFEDWLND DLGSYQGAQG
NRYVGFGNTP PPQKKEDDFL NNAMSSLYSG WSSFTTGASR FASAAKEGAT KFGSQASQKF
WGHKQQPEPA SELGHSLNEN VLKPAQEKVK EGKIFDDVSS GVSQLASKVQ GVSSKGWRDV
TTFFSGKAEG PLDSPSEGHS YQNSGPDHFQ NSSIDQSFWE TFGSTESAKA RKSPSSDSWT
CADTSTERRS SDSWEVWGSA STNRNSNSDG GEGGEGAKKA VPPAVPADDG WDNQNW
//
