ID U3F7E7_CALJA Unreviewed; 678 AA.
AC U3F7E7;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=RNA methyltransferase {ECO:0000256|RuleBase:RU367087};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU367087};
GN Name=MEPCE {ECO:0000313|EMBL:JAB34881.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB34881.1};
RN [1] {ECO:0000313|EMBL:JAB34881.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAB34881.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361, ECO:0000256|RuleBase:RU367087}.
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DR EMBL; GAMQ01006970; JAB34881.1; -; mRNA.
DR AlphaFoldDB; U3F7E7; -.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR039772; Bin3-like.
DR InterPro; IPR010675; Bin3_C.
DR InterPro; IPR024160; BIN3_SAM-bd_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12315:SF0; 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME; 1.
DR PANTHER; PTHR12315; BICOID-INTERACTING PROTEIN RELATED; 1.
DR Pfam; PF06859; Bin3; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51515; BIN3_SAM; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU367087};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00848};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU367087}.
FT DOMAIN 420..675
FT /note="Bin3-type SAM"
FT /evidence="ECO:0000259|PROSITE:PS51515"
FT REGION 1..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 73614 MW; 5712CB6888624B9A CRC64;
MIEMAAEKEP FLVPAPPPPL KDESGGGGGP TVPPHQEAAS RELRCGTERG PGPRAPSAGS
PAFGVGRESP GAAANPRGGP QAQSHGEARL SDPSGRAAPP DVGEERRGGG GTELGPPAPP
RPRNGYQPHR PPGGGGGKRR NSCNVGGGGG GFKHPAFKRR RRVNSDCDSV LPSNFLLGGN
IFDPLNLNSL LDEEVSRALN AETPKSSPLP AKGRDPVEIL IPKDITDPLS LNTCTDEGHV
VLASPLKTGR KRHRHRGQHH QQQQAAGGSE THPVPPTAPL TPSLHGEGTT QHPRHRGQNR
DAPQPYELNT AINCRDEVVS PLPSALQGPS GSLSAPPAAS FTSAPPSSSS RHRKRRRTSS
KSEAGARGGG QGSKEKGRGS WGGRHHQHPL PAAGFKKQQR KFQYGNYCKY YGYRNPSCED
GRLRVLKPEW FRGRDVLDLG CNVGHLTLSI ACKWGPSRMV GLDIYSRLIH SARQNIRHYL
SEELRLPRQT LEGDPGAEGE EGTTTVRKRS CFPASLTASR GPIAAPQVPL DGADTSVFPN
NVVFVTGNYV LDRDDLVEAQ TPEYDVVLCL SLTKWVHLNW GDEGLKRMFR RIYRHLRPGG
ILVLEPQPWS SYGKRKTLTE TIYKNYYRIQ LKPEQFSSYL TSPEVGFSSY ELVATPHNTS
KGFQRPVYLF HKARSPSH
//
