ID U3JW04_FICAL Unreviewed; 273 AA.
AC U3JW04;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=SplA/ryanodine receptor domain and SOCS box containing 4 {ECO:0008006|Google:ProtNLM};
GN Name=SPSB4 {ECO:0000313|Ensembl:ENSFALP00000006958.1};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000006958.1, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000006958.1, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000006958.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SPSB family.
CC {ECO:0000256|ARBA:ARBA00010910}.
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DR RefSeq; XP_005051021.1; XM_005050964.2.
DR RefSeq; XP_005051022.1; XM_005050965.2.
DR RefSeq; XP_005051024.1; XM_005050967.2.
DR RefSeq; XP_005051025.1; XM_005050968.2.
DR RefSeq; XP_016156235.1; XM_016300749.1.
DR RefSeq; XP_016156236.1; XM_016300750.1.
DR AlphaFoldDB; U3JW04; -.
DR STRING; 59894.ENSFALP00000006958; -.
DR Ensembl; ENSFALT00000006987.2; ENSFALP00000006958.1; ENSFALG00000006668.2.
DR GeneID; 101814100; -.
DR KEGG; fab:101814100; -.
DR CTD; 92369; -.
DR eggNOG; KOG3953; Eukaryota.
DR GeneTree; ENSGT01030000234629; -.
DR HOGENOM; CLU_046756_0_1_1; -.
DR OMA; DMPCAGP; -.
DR OrthoDB; 65989at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000016665; Chromosome 9.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd12906; SPRY_SOCS1-2-4; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR PANTHER; PTHR12245:SF3; SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665}.
FT DOMAIN 34..231
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 221..273
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 273 AA; 31123 MW; 79A6A995011B2FBA CRC64;
MGQKISGSIK SVDVREPPYR PVKRELRGPD FCKPARLDML LDMPPAKLEV QYKHAWNNED
RSLNIFVKED DKLTFHRHPV AQSTDCIRGK VGYTRGLHVW QIHWPTRQRG THAVVGVSTA
EAPLHSVGYT SLVGSNSESW GWDLGRNKLY HNCKNQPGVT YPVFLEPDES FVLPDSLLVV
LDMDEGTLSF MVDGQYLGVA FRGLKGKKLY PIVSAVWGHC EITMRYINGL DPEPLPLMDL
CRRSIRFALG RDRLHDIEIL PLPLSLKNYL QYQ
//
