ID U3K532_FICAL Unreviewed; 1460 AA.
AC U3K532;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=RUN and SH3 domain containing 2 {ECO:0000313|Ensembl:ENSFALP00000010136.2};
GN Name=RUSC2 {ECO:0000313|Ensembl:ENSFALP00000010136.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000010136.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000010136.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000010136.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 59894.ENSFALP00000010136; -.
DR Ensembl; ENSFALT00000010176.2; ENSFALP00000010136.2; ENSFALG00000009720.2.
DR eggNOG; ENOG502QR1I; Eukaryota.
DR GeneTree; ENSGT00900000141033; -.
DR HOGENOM; CLU_004141_0_0_1; -.
DR Proteomes; UP000016665; Chromosome Z.
DR CDD; cd17702; RUN_RUSC2; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047342; RUN_RUSC2.
DR InterPro; IPR047343; RUSC1_2.
DR PANTHER; PTHR15591:SF14; AP-4 COMPLEX ACCESSORY SUBUNIT RUSC2; 1.
DR PANTHER; PTHR15591; RUN AND SH3 DOMAIN CONTAINING; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665}.
FT DOMAIN 968..1112
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT REGION 397..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1148..1214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1249..1401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1416..1460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..454
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..491
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..768
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 862..876
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1193..1214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1289..1303
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1357..1371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1460 AA; 159339 MW; 1A7241F656405DBD CRC64;
MDSPPKLTGE TLIVHHIPLV HCQVPDRQCC SVSKRTNPFC QPELSITRTS ALPDRDLSQT
DSLVYSSFLQ TSETSAEASD NKERKARDLI VPSVSKRHNP FLLSEGEDPS IFGDDLGQKS
FHLHNSLIDG KPPFNLQDLA LPPFHLHDSN HIVKSWNMAS RSGVVDGQED KLSSDDIQKR
NNANRCHQAS ERMELDECSC HRGSSSNFSF DSGDQEWNQN AGEPLRNQDA LHRTCSCSSS
EIQHCRCYSS SSQSEVIDQQ MGYISDSSCN SSDGVLVNFS ALYNKMNGQS QSNLNSANLS
CDSSFCSHSD TGAFYLDLHS SPTESKMSCE SHNPENSGKV CGCQHSSSPV LDANCNSYHL
HCEPCTSESS DLTACFQSQA RLVVATQNYY KLVTCDLSSQ SSPSPAGSSI TSCSEDQTKA
SPAQPTEYYL FRRPDLRQEE GNVECSEEEP KGESSQNMIE GQVYVNVSPP NLNTSRQRSR
SYDQNLDRSP GSRLGSLERM VSCPVKLSES PAIPLQSSPP KRVTSFAELA KGRKKNGTSP
PFRPSGDSSL EFSPIPETQR DCPTFLEERA RRSQSLPPMP FIHGLNRSCE GFCLNHAFGD
SQALCSTKDS VSSEKVPSGH GAGGGADSKP VVRYSKDQRP TTLPIQPFVF QHHFSKPPKA
RALHSHFASS LSQLYSLSSS RPASQQISSS QSSALASSAE QAVAGSQGHG TLVTQRSADG
AASRGDGGVK KPGPETTRPS PLGSYSPVRC NVPFFQSVDS SSSPTAERAE DCQPPRSRSC
PISANLLPTR SSPAVSAMQP SKATKSDTLR QKENPKLIPK KEAPLEPSPP LSEYRLHSGS
LPPLSMGGMS MSRVGGHADS HWRSGSETSS SGPLSSMGIR PVNGQSMRQL QLTYNDFFPD
YFSLAEKPPA EFCLSPDGNT ESISIDLLQK KGLVKAINTA VDLIVAHFGT SRDPGVKAKL
GNSSVSPNVG HLILKYLCPA VRDILSDGLK AYVLDMIIGQ RRNIPWSVVE ASTQLGPSTK
LLHSLYSKIS QYTELTNHTM RFNAFIFGLL NIRSLEFWFN HLYNHEDIIL AHYQPVGFLC
LSHSVCQPLF EELLLLLQPL SLLPFNLDLL FEHHLMQMGK EQQQQKELLR VKQDLLLSVH
STLQLMRTRG SSEDPDGCST APETCQGGAR DGDISPGHSP QQAVSEKRVK GVGASCGEGD
REEEQSKMRE SMWEGKKDKQ AGWWYQLMQT SQIYIESSAE GSKFIRSEKK KAALSPAPRP
VQTHKAPPPR EGVVEGAEAC PIAEGTLEER PKAASKPSPE AVEDPVEKPQ QVVVSEEVKE
RSWPFWMGSP PDSVLTELKR SKEKEAQQRV GTAAAAAPQE DSSNSASEGS QPIKWGHLFG
SRKVQKEPRQ PNRLPSGWLS LDKSVFQLVA QTVGASMWRE APPEPDPPHP EPSEAPAVAQ
PAGAVSPHPT CRGPEDGLGQ
//
