ID U3KPJ7_RABIT Unreviewed; 342 AA.
AC U3KPJ7;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=L1 transposable element RRM domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000027157.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000027157.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000027157.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000027157.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; U3KPJ7; -.
DR SMR; U3KPJ7; -.
DR Ensembl; ENSOCUT00000034108.2; ENSOCUP00000027157.2; ENSOCUG00000029650.2.
DR eggNOG; ENOG502SRQ0; Eukaryota.
DR GeneTree; ENSGT01050000244818; -.
DR HOGENOM; CLU_062834_3_0_1; -.
DR InParanoid; U3KPJ7; -.
DR Proteomes; UP000001811; Unplaced.
DR Bgee; ENSOCUG00000029650; Expressed in autopod skin and 2 other cell types or tissues.
DR Gene3D; 3.30.250.20; L1 transposable element, C-terminal domain; 1.
DR Gene3D; 3.30.70.1820; L1 transposable element, RRM domain; 1.
DR Gene3D; 1.20.5.390; L1 transposable element, trimerization domain; 1.
DR InterPro; IPR042566; L1_C.
DR InterPro; IPR035300; L1_dsRBD.
DR InterPro; IPR043636; L1_RRM_dom.
DR InterPro; IPR004244; Transposase_22.
DR PANTHER; PTHR11505; L1 TRANSPOSABLE ELEMENT-RELATED; 1.
DR PANTHER; PTHR11505:SF216; LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN; 1.
DR Pfam; PF17490; Tnp_22_dsRBD; 1.
DR Pfam; PF02994; Transposase_22; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 167..263
FT /note="L1 transposable element RRM"
FT /evidence="ECO:0000259|Pfam:PF02994"
FT DOMAIN 267..330
FT /note="L1 transposable element dsRBD-like"
FT /evidence="ECO:0000259|Pfam:PF17490"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 63..164
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 342 AA; 40345 MW; BAEF6C32FCF1A947 CRC64;
MPSNKHRNRG NKINDDTMMP PNKQNTPNQD YEDDEIEEMQ DTDFKKFMIR TFRSFQKQIL
ELQKSLLDKT ENLSRENEIL RKNQNETQKL VEQESVIVKR NQNEMKSSID QMTNTLESLK
NRVSETEERI SDLKDRAQEN IQSNQRKEEE IRNLKNIVGN LQDTIKKPNI QVLGVPEGME
REKGLEGLFS EILAENFPGL EKDRDILVQE AHRTPNKHDQ KRFSPRHVVI KLTTVKHKEK
ILKCAREKRQ ITLRRSPIRP TADFSSETLQ PRREWQDIAQ VLREKNCQPR ILYPAKLSFV
NEGEIKTFHS KQKLKDYVAT RPALQKILKD VLYSETQKHG HQ
//
