ID U4PBS3_CAEEL Unreviewed; 1248 AA.
AC U4PBS3;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=PDZ domain-containing protein {ECO:0000313|EMBL:CDH93178.1};
GN Name=par-3 {ECO:0000313|EMBL:CDH93178.1,
GN ECO:0000313|WormBase:F54E7.3l};
GN ORFNames=CELE_F54E7.3 {ECO:0000313|EMBL:CDH93178.1}, F54E7.3
GN {ECO:0000313|WormBase:F54E7.3l};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CDH93178.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CDH93178.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CDH93178.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284603; CDH93178.1; -; Genomic_DNA.
DR RefSeq; NP_001293672.1; NM_001306743.1.
DR AlphaFoldDB; U4PBS3; -.
DR SMR; U4PBS3; -.
DR EnsemblMetazoa; F54E7.3l.1; F54E7.3l.1; WBGene00003918.
DR AGR; WB:WBGene00003918; -.
DR WormBase; F54E7.3l; CE49082; WBGene00003918; par-3.
DR OrthoDB; 5405986at2759; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00003918; Expressed in pharyngeal muscle cell (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; U4PBS3; baseline and differential.
DR CDD; cd00992; PDZ_signaling; 3.
DR Gene3D; 2.30.42.10; -; 3.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR16484:SF17; BAZOOKA, ISOFORM B; 1.
DR PANTHER; PTHR16484; PARTITIONING DEFECTIVE 3 RELATED; 1.
DR Pfam; PF00595; PDZ; 3.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR PROSITE; PS50106; PDZ; 3.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:U4PBS3,
KW ECO:0007829|PeptideAtlas:U4PBS3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 302..379
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 436..506
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 580..671
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 688..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 854..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1219..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..785
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 871..886
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1144..1170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1248 AA; 135361 MW; 2175EB17FA0D079E CRC64;
MHNGRGGRYD VCPPPPPPPY HFNHVHTPPS KVIVQQQKQQ QKAHREPPPS YPASKMTTTN
DNVTILAITD EANGGSTTPT YSQIQKQQHH YAQPLPYARK FDGGPSTPIA SAFGSVTVNH
QAHRAASPYN VGFARSNSRD FAPQPTHSKE RRDSVVEVSS FDQIPQSGLR VSTPKPSRQS
EDVIDGKPMN QPILRSSLRT EASGSRTEEA TPVKQSRVTL SPEVEKKLAE QDERKSERRK
HYDKNPGRFA RGSDRKSRIT DALLDARDRI ADQLESQNPA EETKSQMIRV KIDQGPMPGT
SLVTFPPIPE KSENEKQLGI EVNAVFDESS ELPGTSEPTK LSSVQIMKIE DGGRIAKDGR
IRVGDCIVAI DGKPVDQMSI IRVRASISDL AAVTSRPVTL IINRSLESFL EQESSAKPIQ
SALQQANTQY IGHTTVVELI KSSNGFGFTV TGRETAKGER LFYIGTVKPY GVALGHLKSG
DRLLEINGTP TGQWTQSEIV EKLKETMVGE KIKFLVSRVS QSAIMSTSAS SENKENEETL
KVVEEEKIPQ KLPLPALMTP PVPKDTPALS PSGASRFEIV IPFINGSSSA GLGVSLKARV
SKKSNGSKVD CGIFIKNVMH GGAAFKEGGL RVDDRIVGVE DIDLEPLDNR EAQAALAKKL
KEVGMISSNV RLTISRYNEC NPGQISRDLS RITVDASSPS PSSRMSSHTA PDSLLPSPAT
RGTSSSGADS SHSRQSSASS AVPAVPARLT ERDSIVSDGT SRNDESELPD SADPFNREGL
GRKSLSEKRG MGAAADPQHI KLFQDIKHQR QNSDMLNRRS QSMESINRPV ESILRGTGQI
PTGSSSKVQF MQAASPDQHP FPPGAALLRL KNEESRSRDK SRRKSMGNAM RNFFGFGSKS
RDASPEKTPT ESVQLRSVER PKSIIDERNN GSSERAPPPL PPHQSQRRGS GGNVFVDYGE
PYGLIPQYPH NTTSGYESYA DSELYDRYAA HRYHPRGGPI IDEDEYIYRQ QSTSGNSPIN
TSSYVNYGLP ASNAYHVGSR IPPQTSSGSI SKTSGAMRRV YPAEYDEDVA YHQQIPQQST
RYQQGSGSGR GNADYHHMFN SWFAYTGGGA VGAAPVIKSS YGSSPVRIAA ASAIERGESF
VVEPVSGSSA SATDRRGRST SSGAVASGSS STGFQYAAKE KYADARSGKF NGGSTRLFIP
RHGGGLSAAA FATNFGGEAY ETRGGGAGGS PSQYRRRDQG PPHRFPQY
//
