ID   U4QR12_9BACT            Unreviewed;       813 AA.
AC   U4QR12;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Putative ATP-dependent Clp protease, ATPase subunit {ECO:0000313|EMBL:EIJ76073.1};
GN   ORFNames=C75L2_00610002 {ECO:0000313|EMBL:EIJ76073.1};
OS   Leptospirillum sp. Group II 'C75'.
OC   Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC   Leptospirillum.
OX   NCBI_TaxID=1159328 {ECO:0000313|EMBL:EIJ76073.1, ECO:0000313|Proteomes:UP000016760};
RN   [1] {ECO:0000313|EMBL:EIJ76073.1, ECO:0000313|Proteomes:UP000016760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22539719; DOI=10.1126/science.1218389;
RA   Denef V.J., Banfield J.F.;
RT   "In situ evolutionary rate measurements show ecological success of recently
RT   emerged bacterial hybrids.";
RL   Science 336:462-466(2012).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH660589; EIJ76073.1; -; Genomic_DNA.
DR   AlphaFoldDB; U4QR12; -.
DR   HOGENOM; CLU_005070_4_1_0; -.
DR   Proteomes; UP000016760; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 2.
DR   Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 4.10.860.10; UVR domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001943; UVR_dom.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF81923; Double Clp-N motif; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS50151; UVR; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Hydrolase {ECO:0000313|EMBL:EIJ76073.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protease {ECO:0000313|EMBL:EIJ76073.1};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW   ProRule:PRU01251}.
FT   DOMAIN          2..145
FT                   /note="Clp R"
FT                   /evidence="ECO:0000259|PROSITE:PS51903"
FT   DOMAIN          417..452
FT                   /note="UVR"
FT                   /evidence="ECO:0000259|PROSITE:PS50151"
SQ   SEQUENCE   813 AA;  91805 MW;  2CE597F888FBE6B1 CRC64;
     MMDKFTEKGR KVIIMAREEA EKHQNDYLGT EHIVLALVRE QDGIPVAVLK RMGLTPDQIR
     MEIERNLLGG TSTLTFGELP LTPRVKKVIE YSVDEARLLG HTHIGSEHLL LGVLREEDGI
     GGKILRALGA NLMAARQLTA SLLKRANTNV SREKERKSNT PALDDFGRDL TQMASEGQLD
     PVIGRYDEIE RVLQILGRRT KNNPVLIGES GVGKTAIVEG LAQRIVNAEV PDNLLNKRVI
     ALDLGSLVAG TKYRGQFEER LKIVMKEVVT AGNIIIFIDE LHTLVGAGAA EGSIDASNML
     KPALSRGEIQ CIGATTLDEY RKYIEKDGAL KRRFQSIFVD EPPIEEAERI IHGLRDRYEE
     HHGVQITDEA IHDAVTLSER YVTDRFLPDK AIDIIDEAGS RAKLKSFSLP EEIKELDQSL
     KKVVREKEKA IRVQNFEEAV RLRAQEDMLK KQGEDEKRKW KEEQEKNRPT IGREEVSVIV
     SKMTGIPLYK IEEGESERLL KLEGELHRRI VGQEEALSAV ARAIRRSRAG IKGEKRPIGS
     FIFLGPTGVG KTELARTLAE TLFGDEDALI RVDMSEYMER FNVSRLTGAP PGYVGYEEGG
     QLTERVRRRP YSVVLFDEIE KAHPDMFNVL LQILDDGYIT DSLGRKVDFK NTVLIMTSNL
     GARSIEKEGS LGFQRAGIDS KEKFVRDSIH EELRRTFNPE FLNRVDEIVI FHPLAEAHLE
     AIVDLRIADL NKRLGEKGLV VEIDPEVRKW LVKEGYEPHY GARPMRRAIQ RHIEDRLSEM
     IIGGRFKESQ KIRVVLREGQ PVFLEEDVMA GIS
//