ID U4TT03_9LACO Unreviewed; 255 AA.
AC U4TT03;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Segregation and condensation protein A {ECO:0000256|HAMAP-Rule:MF_01805};
GN Name=scpA {ECO:0000256|HAMAP-Rule:MF_01805,
GN ECO:0000313|EMBL:ERL66560.1};
GN ORFNames=L248_0239 {ECO:0000313|EMBL:ERL66560.1};
OS Schleiferilactobacillus shenzhenensis LY-73.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Schleiferilactobacillus.
OX NCBI_TaxID=1231336 {ECO:0000313|EMBL:ERL66560.1, ECO:0000313|Proteomes:UP000030647};
RN [1] {ECO:0000313|Proteomes:UP000030647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LY-73 {ECO:0000313|Proteomes:UP000030647};
RX PubMed=24265500;
RA Lin Z., Liu Z., Yang R., Zou Y., Wan D., Chen J., Guo M., Zhao J., Fang C.,
RA Yang R., Liu F.;
RT "Whole-Genome Sequencing of Lactobacillus shenzhenensis Strain LY-73T.";
RL Genome Announc. 1:e00972-e00913(2013).
CC -!- FUNCTION: Participates in chromosomal partition during cell division.
CC May act via the formation of a condensin-like complex containing Smc
CC and ScpB that pull DNA away from mid-cell into both cell halves.
CC {ECO:0000256|HAMAP-Rule:MF_01805}.
CC -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC Smc. The presence of the three proteins is required for the association
CC of the complex with DNA. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805}.
CC Note=Associated with two foci at the outer edges of the nucleoid region
CC in young cells, and at four foci within both cell halves in older
CC cells. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000256|HAMAP-
CC Rule:MF_01805}.
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DR EMBL; KI271582; ERL66560.1; -; Genomic_DNA.
DR RefSeq; WP_022528186.1; NZ_KI271582.1.
DR AlphaFoldDB; U4TT03; -.
DR STRING; 1231336.L248_0239; -.
DR eggNOG; COG1354; Bacteria.
DR HOGENOM; CLU_038686_3_1_9; -.
DR OrthoDB; 9811016at2; -.
DR Proteomes; UP000030647; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.250.2410; -; 1.
DR HAMAP; MF_01805; ScpA; 1.
DR InterPro; IPR003768; ScpA.
DR PANTHER; PTHR33969; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR PANTHER; PTHR33969:SF2; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR Pfam; PF02616; SMC_ScpA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_01805};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_01805};
KW Chromosome partition {ECO:0000256|HAMAP-Rule:MF_01805};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805}.
SQ SEQUENCE 255 AA; 28646 MW; 77B503CED2F5AAA9 CRC64;
MTALPLTFSV QDYTGPLDLL LHLIRQQKID IYDIPIAQIT SQYLDFIHHQ EVLVLDSAGD
YLVLASTLMA IKSKMLLPDN PLTAADDEEP DDPRENLVNQ LLVYESYQKV AGILRDMAAD
RAKCYDREPQ TPPAATAQPL APGLLTIDAL RLTMERIWQR QRAPRMPRRT IPLEKHVLAT
QMKRISSFLQ NLGPHRPVSF GRLLSDAPTV DEVVTTFLAV LELLKDATVA CTQESFAAPL
YVEWRPTETA KGMIS
//
