ID U4UID7_DENPD Unreviewed; 592 AA.
AC U4UID7;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=D910_10090 {ECO:0000313|EMBL:ERL92782.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL92782.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL92782.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KB632335; ERL92782.1; -; Genomic_DNA.
DR AlphaFoldDB; U4UID7; -.
DR STRING; 77166.U4UID7; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF67; LAMININ SUBUNIT ALPHA-LIKE PROTEIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF02210; Laminin_G_2; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00409; IG; 1.
DR SMART; SM00282; LamG; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 27..196
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 207..425
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 421..459
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 462..497
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 93..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 430..447
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 449..458
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 466..476
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 487..496
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 592 AA; 65527 MW; C84D7353F47307E0 CRC64;
MLYLRNSVDW FFVGNCLEVK SLPTPLPALH ISPEVPEYPV GANVDLRCQS NEPGVIPAWS
KLGGGLADNV QNRAGRLTIY NAKTENEGTY RLGRPAKGRG ALASPTSQTP LLSHPGMQHR
PGGTRLLLLE QTGRQPTVQR RRIQRRFPPP VPVISRSINQ SINGLSLQKS IQLNSVGAID
AGTYICTANS QQRTLDVAIV LVVTGIIPYF TQAPNSYITL PTLPDAYLQF SFEVSFKPEN
NYGLILYNGH REKERDGDFI SLSLDNGVPE FKINLGPGTA TTTVRGNGTL GERQWHTIKV
VRNKKRSKWL AEGEQTLIDR GWAAVIMFVD GAGPFIGENE GKYYGLDLAE PLFLGGVPDY
DNISPEVNID VGLVGEQRFV RRYWASPFYA ALFAGCISKF KIGYNFQDIL RDALNSTGIT
NCETCTENKC QHRGTCQEAL TTEGYTCICS AMFSGPTCDK RKGEACSPYA CGVGKCIDTD
YGFQCQCPLG RSGRNCEKTV QVYEPAFRDN AYIAYPPPRP LKRTKIQMRI KPRSVDDGVL
LYAAETAEGH GDFISLTIKD RHLEFRFDNG KEVVCLNAYT VLIRTRSVLP QN
//
