ID U4V0I7_DENPD Unreviewed; 808 AA.
AC U4V0I7;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
DE Flags: Fragment;
GN ORFNames=D910_01394 {ECO:0000313|EMBL:ERL96201.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL96201.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL96201.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR EMBL; KI210219; ERL96201.1; -; Genomic_DNA.
DR AlphaFoldDB; U4V0I7; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11785:SF531; AMINO ACID TRANSPORTER; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 188..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..625
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 725..743
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 755..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 273..331
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 424..496
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ERL96201.1"
SQ SEQUENCE 808 AA; 91795 MW; BC30BEA879E66907 CRC64;
NISRQGSFRK GHAKKESISD LAQQELKSLF NKTKKSISSA AQRGRERFRK YEQQLAKRSQ
SAPQKFVEEL QESLEKVQHN DASLRRKYSD SDFTVASKAA FELSPQMQLQ LLRQRKPPLA
SAKIIEVLDA KTCSVVQRKC IAASGKTKQV VLSSFRTLSI RELFRNYQIH KRQFHREYNQ
IKRTFRRCCC ELFLIMVFCG LGGLMFKFTE GTFETYYKCG VKRVKRDFID LLWLKSHNLR
EDDWKSLARS RLRKFEEELH SAHEAGMTDY SGMRSWSFLN GIVYCLTILT TIGYGHMFPK
THTGRALTIV YALIGIPLFL IALTDFGKLF TRGIKFVWSF VRRLYYTGSC RKVRKNANMD
DIFKGAQNLY DYATFKRPSL FDPTSPMPPE SESQQQTETP TTPAISNFEI DDEFNLPISV
ALFILVSYIF CGAVMYMVIE KWNFFEAFYF VFISMSTIGF GDYVPRDPVF MIGSIIYLVF
GLALMSMCIN VVQAKLSDTF KQASSKIGAT IGLEVDEEGS VIMAAPENIE EITPVRVEIA
NEGLLASPQW SSIDRPSQPR FAKNVSRFFL WETASANVHV QLNGMVADMD DEKKHDEEIT
LKPKMTLING ITVIVGSIIG SGIFVSPSGV LKNTGSVNVS LLVWTISGVF SMVGAYCYAE
LGTMIRKSGA DYAYIMETFG PFMAFIRLWI ECMIVRPCSQ AIVALTFSQY VMKPLFVDCD
PPDNAARLLA ACCIFVLTFV NCYDVRWATR VQDVFTYAKL LALFIIIAAG IYQLYQGHYS
NFSFINTKTE VTSLALSFYS GLFAYNGW
//
