ID   U5EDN7_NOCAS            Unreviewed;       291 AA.
AC   U5EDN7;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAD85455.1};
GN   ORFNames=NCAST_31_01510 {ECO:0000313|EMBL:GAD85455.1};
OS   Nocardia asteroides NBRC 15531.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=1110697 {ECO:0000313|EMBL:GAD85455.1, ECO:0000313|Proteomes:UP000017048};
RN   [1] {ECO:0000313|EMBL:GAD85455.1, ECO:0000313|Proteomes:UP000017048}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 15531 {ECO:0000313|EMBL:GAD85455.1,
RC   ECO:0000313|Proteomes:UP000017048};
RX   PubMed=24884595; DOI=10.1186/1471-2164-15-323;
RA   Komaki H., Ichikawa N., Hosoyama A., Takahashi-Nakaguchi A., Matsuzawa T.,
RA   Suzuki K., Fujita N., Gonoi T.;
RT   "Genome based analysis of type-I polyketide synthase and nonribosomal
RT   peptide synthetase gene clusters in seven strains of five representative
RT   Nocardia species.";
RL   BMC Genomics 15:323-323(2014).
CC   -!- SIMILARITY: Belongs to the HIBADH-related family.
CC       {ECO:0000256|ARBA:ARBA00009080}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAD85455.1}.
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DR   EMBL; BAFO02000031; GAD85455.1; -; Genomic_DNA.
DR   RefSeq; WP_019049920.1; NZ_VBUS01000001.1.
DR   AlphaFoldDB; U5EDN7; -.
DR   STRING; 1824.SAMN05444423_101544; -.
DR   eggNOG; COG2084; Bacteria.
DR   OrthoDB; 4029976at2; -.
DR   Proteomes; UP000017048; Unassembled WGS sequence.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR048666; RedAm-like_C.
DR   PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   Pfam; PF21761; RedAm-like_C; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017048}.
FT   DOMAIN          9..156
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          164..288
FT                   /note="NADPH-dependent reductive aminase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21761"
SQ   SEQUENCE   291 AA;  31042 MW;  80B4469380FE12E2 CRC64;
     MSEQSTRSVS VLGLGPMGQA MVRALLAAGV EVTVWNRSTE KVDAMVALGA KRADSVAEAL
     AANTVSVLSL THYAAMYDVL GQAPEALAGK VIANLSSDSP EKARAGAAWV RERGAEFLSG
     GVMSAGDNIE HPASYIFYSG PKEVFDAHAE LLRPLSPQEY LGTDDGLAQV FYQALLTTFH
     PWLLSFDQAT AMIAQSGHDI AQFVPFAIRS SQAYPYFMEQ FSEANQNGGW ADLASLKMMV
     AGAQHIIDAS EEVGVDAAFS HLSQSYWRKA VAASEAAGKP VSTYELLRGT D
//