ID U5EF76_NOCAS Unreviewed; 371 AA.
AC U5EF76;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Putative TetR family transcriptional regulator {ECO:0000313|EMBL:GAD83834.1};
GN ORFNames=NCAST_20_04040 {ECO:0000313|EMBL:GAD83834.1};
OS Nocardia asteroides NBRC 15531.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1110697 {ECO:0000313|EMBL:GAD83834.1, ECO:0000313|Proteomes:UP000017048};
RN [1] {ECO:0000313|EMBL:GAD83834.1, ECO:0000313|Proteomes:UP000017048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 15531 {ECO:0000313|EMBL:GAD83834.1,
RC ECO:0000313|Proteomes:UP000017048};
RX PubMed=24884595; DOI=10.1186/1471-2164-15-323;
RA Komaki H., Ichikawa N., Hosoyama A., Takahashi-Nakaguchi A., Matsuzawa T.,
RA Suzuki K., Fujita N., Gonoi T.;
RT "Genome based analysis of type-I polyketide synthase and nonribosomal
RT peptide synthetase gene clusters in seven strains of five representative
RT Nocardia species.";
RL BMC Genomics 15:323-323(2014).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD83834.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BAFO02000020; GAD83834.1; -; Genomic_DNA.
DR AlphaFoldDB; U5EF76; -.
DR STRING; 1824.SAMN05444423_1011139; -.
DR eggNOG; COG1309; Bacteria.
DR Proteomes; UP000017048; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF00440; TetR_N; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS50977; HTH_TETR_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000017048};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..49
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DOMAIN 190..251
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 12..31
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 371 AA; 40137 MW; 4365916E0A184AA7 CRC64;
MAFGAAGYHG VSMEDIAAGL GISSAALYRH YPSKYALFRE ELLRVGNAFT TSIEVPADAT
LTAAERLRHM LTGLVGATVE NRSTVTLVRW EGRYLEPADR LVLDEQRATV LAAFDTQLAI
LRPELAAPDL RMLSTAMFGV ITSIADHHAA LPARTLNRLL GAACLALIDD ELPPAAVNSE
QAAQIEIPES FKHELLLRKA VELFHERGYP NVSVEDIASA AGLSAASAVY RFYRGKSDIL
AAAFRRAADR VSGAIGPAVA GTDGSAAALD VLIEQFVADT FDERALAVVY YAEFGHVPAE
ERAVLRNIQR LSVQEWARLV REERPELSAA EARFLVHAAF AMVIDLGQAF GPDPVASRAR
VSHLMHRVLL G
//
