ID   U5EN07_9DIPT            Unreviewed;       619 AA.
AC   U5EN07;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Putative phosphoglucomutase/phosphomannomutase {ECO:0000313|EMBL:JAB59088.1};
OS   Corethrella appendiculata.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Chaoboridae;
OC   Corethrella.
OX   NCBI_TaxID=1370023 {ECO:0000313|EMBL:JAB59088.1};
RN   [1] {ECO:0000313|EMBL:JAB59088.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Salivary glands {ECO:0000313|EMBL:JAB59088.1};
RA   Ribeiro J.M.C., Chagas A.C., Pham V.M., Lounibos L.P., Calvo E.;
RT   "An insight into the sialome of the frog biting fly, Corethrella
RT   appendiculata.";
RL   Insect Biochem. Mol. Biol. 44:23-32(2014).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC       {ECO:0000256|ARBA:ARBA00010231}.
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DR   EMBL; GANO01000783; JAB59088.1; -; mRNA.
DR   AlphaFoldDB; U5EN07; -.
DR   GO; GO:0016868; F:intramolecular phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd05799; PGM2; 1.
DR   Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR   InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR   InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR   InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR   InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR   InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR   InterPro; IPR016066; A-D-PHexomutase_CS.
DR   InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR   PANTHER; PTHR45745:SF1; PHOSPHOGLUCOMUTASE 2A-RELATED; 1.
DR   PANTHER; PTHR45745; PHOSPHOMANNOMUTASE 45A; 1.
DR   Pfam; PF02878; PGM_PMM_I; 1.
DR   Pfam; PF02879; PGM_PMM_II; 1.
DR   Pfam; PF02880; PGM_PMM_III; 1.
DR   PRINTS; PR00509; PGMPMM.
DR   SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR   SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
DR   PROSITE; PS00710; PGM_PMM; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          55..193
FT                   /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF02878"
FT   DOMAIN          242..334
FT                   /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF02879"
FT   DOMAIN          373..471
FT                   /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF02880"
SQ   SEQUENCE   619 AA;  70281 MW;  03F31F590DDD7CE3 CRC64;
     MALNGVQIES DSIELNQKIS EWLKWDKNEN TLNEIKSLVN DKKWDILKPR LLKRLAFGTA
     GLRGVMQAGF NSMNDLVVIQ SAQGLCKYIL ECYPEDVDRK RGIVLGYDGR YNSKRFAELS
     ACIFLNAKIP VYLYGRTVAT PFIPFCVREK NCLAGVMVTA SHNPKEDNGY KVYWTNSAQI
     ISPHDKNIQA NILANLVPQE ESWNVDMLQK SKQLFDPYDE MTSLYYEKLF KNIPKRFIDE
     YNNQSENALE FVYTAMHGVG YPFIEKSFEI TKLKSVIAVQ EQRDPDPEFP TVKFPNPEEG
     KSSLVLSIKL ANERNCRVIL ANDPDADRLA CAEKGHNNEW RVFTGNELGA LLGWWTIHCY
     REENPGKSLT DCYFLASTVS SKMLRSIAKI EGLNFEETLT GFKWMGNKSV DLMNEGRTVL
     FAFEEAIGFM VSPTVLDKDG VSAATHLATM CNYLQQTSGQ SLSDKLNELY DIYGFHYTIT
     SYLFCYDPNT IERIFTRIRT FEDGAIDTYP RSIGTGDDTY EIESVRDLTT GKDTSQADGI
     ALLPASKSSQ MITFSFVNGA VITLRTSGTE PKIKYYAEMC AQPGQRDWTS SRELLQKMAN
     TIVEELFEPE KNNLTRRSD
//