ID   U5ES00_9DIPT            Unreviewed;       784 AA.
AC   U5ES00;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Putative peroxinectin-like protein {ECO:0000313|EMBL:JAB57279.1};
OS   Corethrella appendiculata.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Chaoboridae;
OC   Corethrella.
OX   NCBI_TaxID=1370023 {ECO:0000313|EMBL:JAB57279.1};
RN   [1] {ECO:0000313|EMBL:JAB57279.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Salivary glands {ECO:0000313|EMBL:JAB57279.1};
RA   Ribeiro J.M.C., Chagas A.C., Pham V.M., Lounibos L.P., Calvo E.;
RT   "An insight into the sialome of the frog biting fly, Corethrella
RT   appendiculata.";
RL   Insect Biochem. Mol. Biol. 44:23-32(2014).
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DR   EMBL; GANO01002592; JAB57279.1; -; mRNA.
DR   AlphaFoldDB; U5ES00; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   CDD; cd09823; peroxinectin_like; 1.
DR   Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR   InterPro; IPR019791; Haem_peroxidase_animal.
DR   InterPro; IPR010255; Haem_peroxidase_sf.
DR   InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR   PANTHER; PTHR11475:SF142; CHORION PEROXIDASE; 1.
DR   PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR   Pfam; PF03098; An_peroxidase; 1.
DR   PRINTS; PR00457; ANPEROXIDASE.
DR   SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR   PROSITE; PS50292; PEROXIDASE_3; 1.
PE   2: Evidence at transcript level;
KW   Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..784
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004659636"
FT   BINDING         545
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ   SEQUENCE   784 AA;  89590 MW;  8389572185715054 CRC64;
     MTPMIKFWCL TLMFQLFKLT CALVTIEKPH LPHNHLTDYD KIPDRCTTNN NNNKCVKPIQ
     CPAHLHMNEI SFCSMPESTV GICCTTGYNH SFEGHYKIFK RSISENSNNN QIYKAIENGK
     ETFAETLEYF DNKSDIIGKE NTDFHAQFFK PSDNKLEEAA RNNKAVEEIF IETALEELRR
     LSVQETDLNT FGETDDKTTK TKRCILEASC TNVNRRYRRV DGRCNNPLPG RGLWGSSGFP
     MERLLPPAYE DSIWKPRQNS VLGGKLLSPR TISRKLLPDV DRPHPKLNLL TMQFGQFITH
     DVSQSASITL TNGQPIECCG NNGSTILPPN LLHFACLPIS IDPNDEFYSK FNQRCMNFVR
     SQLVSNQDCK IGYGKQLSRA THFIDGSIIY GTTVRLLATL RTFSGGKLRV FNHLNRELLP
     QTNNRTQCET FARACFVAGD SRVNQIISLT AVQTLFLREH NRIAGILSSL NPHWKDETIF
     QETRRLIIAK LQHIAFNEYL PLIIGHKNFR VFSLNEPKGY SKSYNPDINP SITNEFSAAA
     FRFGHSTVDG KFFVHDKNRL DEIIEIPDVM LEPSRLLHLN FYDEIFRTLT NQPMQSVDDS
     ITRGLSQFLF RGRNPFGFDL ASLNIQRGRD HGLRPYNDYL ELGGRKKINT FAEYGDEVGP
     LLEQVYKSPH DVDLWIGGLM ERAKHGSIFG PTFSEIIADQ FVRFKSGDRY YYKNGPEVNP
     GFFTPKQLNE IEKTSIARII CDNSDRIALF EQAPHGFVLP HEGNKPVPCD SNIIPTLDYS
     FWKD
//