ID U5ETK6_9DIPT Unreviewed; 648 AA.
AC U5ETK6;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 03-MAY-2023, entry version 36.
DE SubName: Full=Putative ca2+-binding actin-bundling protein {ECO:0000313|EMBL:JAB57999.1};
DE Flags: Fragment;
OS Corethrella appendiculata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Chaoboridae;
OC Corethrella.
OX NCBI_TaxID=1370023 {ECO:0000313|EMBL:JAB57999.1};
RN [1] {ECO:0000313|EMBL:JAB57999.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary glands {ECO:0000313|EMBL:JAB57999.1};
RA Ribeiro J.M.C., Chagas A.C., Pham V.M., Lounibos L.P., Calvo E.;
RT "An insight into the sialome of the frog biting fly, Corethrella
RT appendiculata.";
RL Insect Biochem. Mol. Biol. 44:23-32(2014).
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DR EMBL; GANO01001872; JAB57999.1; -; mRNA.
DR AlphaFoldDB; U5ETK6; -.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR CDD; cd21292; CH_PLS_rpt1; 1.
DR CDD; cd21295; CH_PLS_rpt2; 1.
DR CDD; cd21298; CH_PLS_rpt3; 1.
DR CDD; cd21301; CH_PLS_rpt4; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR PANTHER; PTHR19961:SF18; FI19014P1; 1.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR Pfam; PF00307; CH; 4.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00033; CH; 4.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 4.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 2: Evidence at transcript level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 7..42
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 118..234
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 262..367
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 384..492
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 505..613
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 623..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB57999.1"
SQ SEQUENCE 648 AA; 72688 MW; 6EEDE2F712FE0B10 CRC64;
QKKLSADELL EIKEKFTEID TNKDGFIELK ELKDALDQVG FKIPGYQVRQ MIDEYSNKQR
SQNTGKLSYD EFETLCLDLK SKDVGTTFKA VVSKKENLET LGGMSDSSAA GTTHSVRLEE
QLAFSDWINS NLGYDQDLKH LLPLDSEGKL LYEKIKDGIL LCKIINHSCP DTIDERAINK
KNLTVYTKFE NLTLALVSSQ AIGCNIVNID AHDLAKGKPH LVLGLLWQII RIGLFSHITL
DSCPGLATLL SDGERLEDLM KLSPEAILLR WVNHHLERAG VSRRCTNFQS DISDSEIYTY
LLKQIAPQDA GVTVEALREQ NLANRAEVML QQAAKLNCRS FVTPQDVVNG VYKLNLAFVA
NLFNNHPGLD QPDEIEGLET IEETREEKTY RNWMNSMGVK PHVNWLYSDL ADGLIIFQLF
DIISPGIVNW KRVHQKFTPL RKFMEKLENC NYAVELGKQL KFSLVGIAGQ DLNDGNATLT
LALIWQLMRA YTLSILSRLA NTGNPIIEKE IVLWVNTKLA NARKTTSLRN FQDSAISDGK
IIIDLIDSIK QGSINYDNVK EGTTEEEKLE NAKYAISMAR KIGARVYALP EDITEVKSKM
IMTVFACLMA MDYIPNMDTV QPTTNGNGTT SPPAIVTNGN GVDHHLEN
//
