ID U5FJG5_POPTR Unreviewed; 548 AA.
AC U5FJG5;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE RecName: Full=Cystathionine gamma-synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=POPTR_017G086500 {ECO:0000313|EMBL:PNS95926.1};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNS95926.1, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNS95926.1, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
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DR EMBL; CM009306; PNS95926.1; -; Genomic_DNA.
DR RefSeq; XP_006373333.1; XM_006373271.1.
DR AlphaFoldDB; U5FJG5; -.
DR STRING; 3694.U5FJG5; -.
DR EnsemblPlants; Potri.017G086500.1.v4.1; Potri.017G086500.1.v4.1; Potri.017G086500.v4.1.
DR GeneID; 7482488; -.
DR Gramene; Potri.017G086500.1.v4.1; Potri.017G086500.1.v4.1; Potri.017G086500.v4.1.
DR KEGG; pop:7482488; -.
DR eggNOG; KOG0053; Eukaryota.
DR InParanoid; U5FJG5; -.
DR OrthoDB; 6018at2759; -.
DR Proteomes; UP000006729; Chromosome 17.
DR ExpressionAtlas; U5FJG5; baseline and differential.
DR GO; GO:0003962; F:cystathionine gamma-synthase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR044639; CGS1/2.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR43379; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR43379:SF1; CYSTATHIONINE GAMMA-SYNTHASE 1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|RuleBase:RU362118};
KW Reference proteome {ECO:0000313|Proteomes:UP000006729}.
FT REGION 21..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 58644 MW; C5D0594BA817FAFF CRC64;
MAVSSCPCPK LFVASSFECR SDSSSSADQP SQGRSNSARH GTTPFLSGAG MSSLILKFPP
NFVRQLSTKA RRNCSNIGVA QIVAASWSNN SAAGAPSAAA AAAAAAAASA IPAAEPAKTL
AGNEVVGIDS SDNKNVSVVQ LEDLSSDLEY KSFLSSDGSI AVHAGERLGR GIVTDAITTP
VVNTSAYFFK KTQELIDFKE KRHASYEYGR YGNPTTQVLE DKISELEGAE STLILASGMC
ASTVLLLALV PAGGHLVTTT DCYRKTRIFM ETFLPKMGIT VTVIDPADVK ALESALEINK
VSLFFTESPT NPFLRCVDIE LVSELCHRKG ALVCIDGTFA TPLNQKALAL GADLILHSAT
KFIGGHNDVL GGCISGSTKV VSEIRNLHHV LGGTLNPNAA YLIIRGMKTL HLRVQQQNST
ALRMAKILEA HPKVRCVYYP GLPSHPEHHI AKKQMTGFGG VVSFEVDGDL FITSKFVDAL
KIPYIAPSFG GCESIVDQPA IMSYWDLSRS EREKYGIKDN LVRFSFGVED FEDLKADILQ
ALETIESA
//
