ID U5L512_9BACI Unreviewed; 339 AA.
AC U5L512;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:AGX02400.1};
GN ORFNames=N288_02165 {ECO:0000313|EMBL:AGX02400.1};
OS Bacillus infantis NRRL B-14911.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1367477 {ECO:0000313|EMBL:AGX02400.1, ECO:0000313|Proteomes:UP000017805};
RN [1] {ECO:0000313|EMBL:AGX02400.1, ECO:0000313|Proteomes:UP000017805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-14911 {ECO:0000313|EMBL:AGX02400.1,
RC ECO:0000313|Proteomes:UP000017805};
RA Massilamany C., Smith T.P.L., Loy J.D., Barletta R., Reddy J.;
RT "Complete genome sequence of Bacillus infantis NRRL B-14911 that has
RT potential to induce cardiac disease by antigenic mimicry.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP006643; AGX02400.1; -; Genomic_DNA.
DR RefSeq; WP_009792468.1; NC_022524.1.
DR AlphaFoldDB; U5L512; -.
DR STRING; 1367477.N288_02165; -.
DR GeneID; 85550522; -.
DR KEGG; bif:N288_02165; -.
DR PATRIC; fig|1367477.3.peg.374; -.
DR HOGENOM; CLU_026673_29_2_9; -.
DR OrthoDB; 9805663at2; -.
DR Proteomes; UP000017805; Chromosome.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000017805}.
FT DOMAIN 17..333
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 339 AA; 36414 MW; A91EE8F115D77699 CRC64;
MLPNTQQQIQ LASRPKGTPV KDDFRFADVK VEEPKEGEVL LQTVYLSVDP YMRGRMSDAK
SYVEPFKLDE ALHGGGVAKV VKSKSAAFNE GDYIVGMLPW QEYSVASEKA VRKIDPQVAP
VSTHLGILGM PGLTAYFGLL DIGQPKENET VVVSGAAGAV GSAVGQIAKI KGARVVGIAG
SDEKISYLKD ELGFDEAINY KTAGDIREAL EKACPDGIDV YFENVGGEIG DAAISLLNKF
GRVPVCGAIS AYNKQGEDTG PRVQGQLIKT SALMKGFTVG DYASRYKEAA ADLGKWVSEG
KLKYEETVTE GFDNILDAFL GLFEGKNMGK QLVKVAEDK
//
