UniProt: U5L6X4

Database: UniProt
Entry: U5L6X4_9BACI

LinkDB:  U5L6X4_9BACI 
Original site:  U5L6X4_9BACI

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Ontology (3)   
   GO (3)   
Gene (2)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (5)   
   InterPro (4)   
   Pfam (1)   
All databases (12)   

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ID   U5L6X4_9BACI            Unreviewed;       316 AA.
AC   U5L6X4;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Magnesium transport protein CorA {ECO:0000256|RuleBase:RU362010};
GN   Name=corA {ECO:0000256|RuleBase:RU362010};
GN   ORFNames=N288_02685 {ECO:0000313|EMBL:AGX02501.1};
OS   Bacillus infantis NRRL B-14911.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1367477 {ECO:0000313|EMBL:AGX02501.1, ECO:0000313|Proteomes:UP000017805};
RN   [1] {ECO:0000313|EMBL:AGX02501.1, ECO:0000313|Proteomes:UP000017805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-14911 {ECO:0000313|EMBL:AGX02501.1,
RC   ECO:0000313|Proteomes:UP000017805};
RA   Massilamany C., Smith T.P.L., Loy J.D., Barletta R., Reddy J.;
RT   "Complete genome sequence of Bacillus infantis NRRL B-14911 that has
RT   potential to induce cardiac disease by antigenic mimicry.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates influx of magnesium ions.
CC       {ECO:0000256|RuleBase:RU362010}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362010}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
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DR   EMBL; CP006643; AGX02501.1; -; Genomic_DNA.
DR   RefSeq; WP_009792360.1; NC_022524.1.
DR   AlphaFoldDB; U5L6X4; -.
DR   STRING; 1367477.N288_02685; -.
DR   GeneID; 85550617; -.
DR   KEGG; bif:N288_02685; -.
DR   PATRIC; fig|1367477.3.peg.480; -.
DR   HOGENOM; CLU_007127_0_0_9; -.
DR   OrthoDB; 9803416at2; -.
DR   Proteomes; UP000017805; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   CDD; cd12831; TmCorA-like_u2; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   NCBIfam; TIGR00383; corA; 1.
DR   PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU362010};
KW   Ion transport {ECO:0000256|RuleBase:RU362010};
KW   Magnesium {ECO:0000256|RuleBase:RU362010};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017805};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362010};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
SQ   SEQUENCE   316 AA;  37586 MW;  5CA62013F7D82C05 CRC64;
     MIRTIAVTKN HEIKSNWDIT RLLEEDILWY WADFSNPSDA EIELLRKPLN FHPLAIEDCI
     HVLQRPKLDY YEDYAFFVTH SVNPDTIDRE EVNFFLGQNY VITFHHHPST EIEDVRERLR
     LSNSPDKWEP LLVLYHILDK IVDNYFPLVY QLEDTLNDID ENSKDRPMEL LLEDLFDARH
     DLLALRHTVA PMRDLIYRML NSQRLAGFQE KIKYFSDIHD HLLKLAEMIE ENRELTTDIR
     DSYLSLNAHQ TNRVMKVLTV ITTIFMPLTF IAGIYGMNFE HMPELEWDSG YFATLLVMLT
     IGLAMFAWFK KKGWFK
//

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