ID U5N8G3_9BURK Unreviewed; 868 AA.
AC U5N8G3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Cenrod_0440 {ECO:0000313|EMBL:AGX86558.1};
OS Candidatus Symbiobacter mobilis CR.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae.
OX NCBI_TaxID=946483 {ECO:0000313|EMBL:AGX86558.1, ECO:0000313|Proteomes:UP000017184};
RN [1] {ECO:0000313|EMBL:AGX86558.1, ECO:0000313|Proteomes:UP000017184}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR {ECO:0000313|EMBL:AGX86558.1};
RX PubMed=24267588; DOI=10.1186/gb-2013-14-11-r127;
RA Liu Z., Muller J., Li T., Alvey R.M., Vogl K., Frigaard N.U.,
RA Rockwell N.C., Boyd E.S., Tomsho L.P., Schuster S.C., Henke P., Rohde M.,
RA Overmann J., Bryant D.A.;
RT "Genomic analysis reveals key aspects of prokaryotic symbiosis in the
RT phototrophic consortium "Chlorochromatium aggregatum".";
RL Genome Biol. 14:R127-R127(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP004885; AGX86558.1; -; Genomic_DNA.
DR AlphaFoldDB; U5N8G3; -.
DR STRING; 946483.Cenrod_0440; -.
DR KEGG; cbx:Cenrod_0440; -.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_330300_0_0_4; -.
DR Proteomes; UP000017184; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF50; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AGX86558.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000017184};
KW Transferase {ECO:0000313|EMBL:AGX86558.1}.
FT DOMAIN 299..369
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 614..861
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 868 AA; 95994 MW; 220B88B39B9BC253 CRC64;
MVECGQTIIR SRSRGVLFGD VCRHLVDAGG MRAAWVGIWN PLEHRIWPTA RYGKGLGYLQ
ALSLGGKVGV HLGGSLAEQA IARNELVWSD DVTTDPGMES LRELASPLQW RSALVVPLQL
GGAAWGVLNV YAEQGKAFDA GVRSLFEQLS ANISHALDIF ENDAQRREAE FALQESEVRY
NALFASSCMP LIVLDPKSGR IVDANIRALD FYGWNHAGFT SMCVAQIYVC DPETAMRELH
EAAECTFVSL EHRHRLHSGE VRDVEIFSSP IHIDGGKFLI WAVHDVSERK RLHAKMRSAQ
ALTQRFIDHL PGAAFVKDKD LRLIVVNRHL GTMLGAEPHT LVGKTAYDLF PPEFAHNATH
FDQEVLADGK SRTMDEFFEG RHAETTLFVM EDDTGERFLG GLSIDVTDPG RIRERTRGLL
QLNEFASKMD EPAFLLQGLE SAQSLTSSQI GFLHFVSADQ QHYEMAVWTA STRNFCSADY
PTHGSLHTAG VWADCLRQAC PVIYNDYSTV PHKHGLPEGH PALNRFITVP IMEDGLARIL
IGVGNKRNAY DQIDTDTLLL VGNGMWRIIG RMRAERALQQ RLQEMSALYR DLAEAQSQLL
QSEKLASIGQ LAAGVAHEIN NPIGFIKSNL GSLADYVAKL LDIAKAYAHT EDELEAQGIH
SPAFEELRRR KAEADFDFLL TDLPELIEES REGVERVGKI VMDLKNFARV GDSDFGWADI
HAGLESTINV VWNELKYKAD VVREYGELPL VFCVASQINQ VFMNLLINAA QAMTTRGTIT
VRTGAVGDEV WIEVQDTGCG IDLAKQARIF DPFFTTKPVG QGTGLGLSIA MNIAKQHQGS
LTVQSQPGEG TVFRMTLPVC PVTGNPPQ
//
