ID U5RS19_9CLOT Unreviewed; 111 AA.
AC U5RS19;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Anti-sigma F factor antagonist {ECO:0000256|ARBA:ARBA00020784, ECO:0000256|RuleBase:RU003749};
DE AltName: Full=Stage II sporulation protein {ECO:0000256|RuleBase:RU003749};
GN Name=spoIIAA {ECO:0000313|EMBL:AGY75520.1};
GN ORFNames=CAETHG_1295 {ECO:0000313|EMBL:AGY75520.1};
OS Clostridium autoethanogenum DSM 10061.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1341692 {ECO:0000313|EMBL:AGY75520.1, ECO:0000313|Proteomes:UP000017590};
RN [1] {ECO:0000313|EMBL:AGY75520.1, ECO:0000313|Proteomes:UP000017590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10061 {ECO:0000313|EMBL:AGY75520.1};
RX PubMed=24655715; DOI=10.1186/1754-6834-7-40;
RA Brown S.D., Nagaraju S., Utturkar S., De Tissera S., Segovia S.,
RA Mitchell W., Land M.L., Dassanayake A., Kopke M.;
RT "Comparison of single-molecule sequencing and hybrid approaches for
RT finishing the genome of Clostridium autoethanogenum and analysis of CRISPR
RT systems in industrial relevant Clostridia.";
RL Biotechnol. Biofuels 7:40-40(2014).
CC -!- FUNCTION: In the phosphorylated form it could act as an anti-anti-sigma
CC factor that counteracts SpoIIAB and thus releases sigma f from
CC inhibition. {ECO:0000256|ARBA:ARBA00001976}.
CC -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC {ECO:0000256|ARBA:ARBA00009013, ECO:0000256|RuleBase:RU003749}.
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DR EMBL; CP006763; AGY75520.1; -; Genomic_DNA.
DR RefSeq; WP_013240025.1; NZ_CP012395.1.
DR AlphaFoldDB; U5RS19; -.
DR KEGG; cah:CAETHG_1295; -.
DR PATRIC; fig|1341692.11.peg.1292; -.
DR HOGENOM; CLU_115403_7_0_9; -.
DR Proteomes; UP000017590; Chromosome.
DR GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR GO; GO:0045152; F:antisigma factor binding; IEA:InterPro.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR CDD; cd07043; STAS_anti-anti-sigma_factors; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR003658; Anti-sigma_ant.
DR InterPro; IPR014237; Anti-sigma_F_ant.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00377; ant_ant_sig; 1.
DR NCBIfam; TIGR02886; spore_II_AA; 1.
DR PANTHER; PTHR33495; ANTI-SIGMA FACTOR ANTAGONIST TM_1081-RELATED-RELATED; 1.
DR PANTHER; PTHR33495:SF2; ANTI-SIGMA-B FACTOR ANTAGONIST; 1.
DR Pfam; PF01740; STAS; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Sporulation {ECO:0000256|ARBA:ARBA00022969}.
FT DOMAIN 1..111
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 111 AA; 12400 MW; 417F171F888C5F9C CRC64;
MNLEFNVKDN KLIVYMRGEL DHHSAEEVRN KIDDRLDRES LNKLIMDFSG VSFMDSSGIG
VVIGRYKKLN SADGSVCIVG AINSVKRVFE LSGMFKIIGL YDSVAEALQN I
//
