ID   U5T8J8_COWPX            Unreviewed;       785 AA.
AC   U5T8J8;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Uncoating factor OPG117 {ECO:0000256|ARBA:ARBA00034867};
GN   Name=CPXV122 {ECO:0000313|EMBL:AGY97036.1};
OS   Cowpox virus (CPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=10243 {ECO:0000313|EMBL:AGY97036.1};
OH   NCBI_TaxID=10129; Apodemus sylvaticus (European woodmouse).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH   NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
OH   NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN   [1] {ECO:0000313|Proteomes:UP000097203, ECO:0000313|Proteomes:UP000098423}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BeaBer04/1 {ECO:0000313|EMBL:AGY97036.1}, CatBer07/1
RC   {ECO:0000313|EMBL:AGY99392.1}, CatPot07/1
RC   {ECO:0000313|EMBL:AGZ00245.1}, HumBer07/1
RC   {ECO:0000313|EMBL:AGZ00875.1}, and HumMag07/1
RC   {ECO:0000313|EMBL:AGY97900.1};
RA   Dabrowski P.W., Radonic A., Kurth A., Nitsche A.;
RT   "Genome-wide comparison of cowpoxviruses reveals a new clade related to
RT   Variola virus.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:SNB48899.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Ger/2013/Alpaca {ECO:0000313|EMBL:SNB48899.1};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the orthopoxvirus OPG117 family.
CC       {ECO:0000256|ARBA:ARBA00034752}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KC813491; AGY97036.1; -; Genomic_DNA.
DR   EMBL; KC813495; AGY97900.1; -; Genomic_DNA.
DR   EMBL; KC813502; AGY99392.1; -; Genomic_DNA.
DR   EMBL; KC813506; AGZ00245.1; -; Genomic_DNA.
DR   EMBL; KC813509; AGZ00875.1; -; Genomic_DNA.
DR   EMBL; LT896719; SNB48899.1; -; Genomic_DNA.
DR   Proteomes; UP000097203; Genome.
DR   Proteomes; UP000098423; Genome.
DR   Proteomes; UP000101132; Genome.
DR   Proteomes; UP000151407; Genome.
DR   Proteomes; UP000159199; Genome.
DR   Proteomes; UP000274633; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004968; DNA_primase/NTPase_C.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF03288; Pox_D5; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   3: Inferred from homology;
FT   DOMAIN          477..639
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000259|PROSITE:PS51206"
SQ   SEQUENCE   785 AA;  90416 MW;  AF43D0215E3AB6AF CRC64;
     MDATIRGNDI IFVLKTIGVP SACRQNEDPR FVEAFKCDEL ERYIENNPEC TLFESLRDEE
     AYSIVRIFMD VDLDACLDEI DYLTAIQDFI IEVSNCVARF AFTECGAIHE NVIKSMRSNF
     SLTKSTNRDK TSFHIIFLDT YTTMDTLIAM KRTLLELSRS SENPLTRSID TAVYRRKTTL
     RVVGTRKNPN CDTIHVMQPP HDNIEDYLFT YVDMNNNSYY FSLQRRLEDL VPDKLWEPGF
     ISFEDAIKRV SKIFINSIIN FNDLDENNFT TVPLVIDYVT PCALCKKRSH KHPHQLSLEN
     GAIRIYKTGN PHSCKVKIVP LDGNKLFNIA QRILDTNSVL LTERGDHIVW INNSWKFNSE
     EPLITKLILS IRHQLPKEYS SELLCPRKRK TVEANIRDML VDSVETDTYP DKLPFKNGVL
     DLVDGMFYSG DDAKKYTCTV STGFKFDDTK FVEDSPEMEE LMNIINDIQP LTDENKKNRE
     LYEKTLSSCL CGATKGCLTF FFGETATGKS TTKRLLKSAI GDLFVETGQT ILTDVLDKGP
     NPFIANMHLK RSVFCSELPD FACSGSKKIR SDNIKKLTEP CVIGRPCFSN KINNRNHATI
     IIDTNYKPVF DRIDNALMRR IAVVRFRTHF SQPSGREAAE NNDAYDKVKL LDEGLDGKIQ
     NNRYRFAFLY LLVKWYKKYH IPIMKLYPTP EEIPDFAFYL KIGTLLVSSS VKHIPLMTDL
     SKKGYILYDN VVTLPLTTFQ QKISKYFNSR LFGHDIESFI NRHKKFANVS DEYLQYIFIE
     DISSP
//