ID   U5VZC4_9ACTN            Unreviewed;       527 AA.
AC   U5VZC4;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=SARP family transcriptional regulator {ECO:0000313|EMBL:AGZ41045.1};
GN   ORFNames=AFR_13795 {ECO:0000313|EMBL:AGZ41045.1};
OS   Actinoplanes friuliensis DSM 7358.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ41045.1, ECO:0000313|Proteomes:UP000017746};
RN   [1] {ECO:0000313|EMBL:AGZ41045.1, ECO:0000313|Proteomes:UP000017746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ41045.1,
RC   ECO:0000313|Proteomes:UP000017746};
RX   PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA   Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA   Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT   "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT   HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL   J. Biotechnol. 178:41-42(2014).
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
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DR   EMBL; CP006272; AGZ41045.1; -; Genomic_DNA.
DR   AlphaFoldDB; U5VZC4; -.
DR   STRING; 1246995.AFR_13795; -.
DR   KEGG; afs:AFR_13795; -.
DR   PATRIC; fig|1246995.3.peg.2801; -.
DR   eggNOG; COG2273; Bacteria.
DR   eggNOG; COG3629; Bacteria.
DR   HOGENOM; CLU_490613_0_0_11; -.
DR   Proteomes; UP000017746; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd15831; BTAD; 1.
DR   CDD; cd00413; Glyco_hydrolase_16; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000757; GH16.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR   PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF00722; Glyco_hydro_16; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS51762; GH16_2; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000017746}.
FT   DOMAIN          1..89
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51755"
FT   DOMAIN          305..527
FT                   /note="GH16"
FT                   /evidence="ECO:0000259|PROSITE:PS51762"
FT   DNA_BIND        1..89
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   527 AA;  56113 MW;  453E28C0CA3C5540 CRC64;
     MGPVEVRAPD GSVLAGEPRR LAVLAALAVD AGRVVQATTL IDRVWGDDPP GQAARTLGTY
     VTRIRRMLEQ SGDSSVTVVS QAGGYRLTAG HDQVDLFRFR DLVVGARAPS ITPERRVELL
     RQSVSLHRGD PLTGVSGAWA TRTREQLAGE LLTARAEWAE AELAVGNTTV VLAPLTALVD
     ANPLVEPLVV TLVRALVAAG RPTEALERCR LHQQRLADGY GTDPSPQLKA LYESVLRGDQ
     RPAAVAERSQ VPAAVAVLEP ERPLPAPAVP SRRRRRYVMA AVGVCATLAG ALGAVVVSRP
     PDRITETRFT VTEDFSGTAL TPMQWAANQA ERENGSSWSP GAVRVGGGEV QISGTGRNPT
     GAGNVGGAVC WCLDGGIVRT YGVWEVRARF DVGTGYAPAL GLYSGVDEDT PGWGFMTMGR
     FDDGERRVMY PVVRGAGAEP VDGSPVAGDF TDWNTFSIEW RADFVAISLN GVVVLDTRKL
     PGPVSIPTVP MFLYVQIIPG PEGPVPAPNQ ETPSRVAAHV DWARYTS
//