ID   U5WBA7_9ACTN            Unreviewed;       370 AA.
AC   U5WBA7;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Putative ROK-family protein {ECO:0000313|EMBL:AGZ46493.1};
GN   ORFNames=AFR_41195 {ECO:0000313|EMBL:AGZ46493.1};
OS   Actinoplanes friuliensis DSM 7358.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ46493.1, ECO:0000313|Proteomes:UP000017746};
RN   [1] {ECO:0000313|EMBL:AGZ46493.1, ECO:0000313|Proteomes:UP000017746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ46493.1,
RC   ECO:0000313|Proteomes:UP000017746};
RX   PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA   Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA   Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT   "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT   HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL   J. Biotechnol. 178:41-42(2014).
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
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DR   EMBL; CP006272; AGZ46493.1; -; Genomic_DNA.
DR   RefSeq; WP_023562825.1; NC_022657.1.
DR   AlphaFoldDB; U5WBA7; -.
DR   STRING; 1246995.AFR_41195; -.
DR   KEGG; afs:AFR_41195; -.
DR   PATRIC; fig|1246995.3.peg.8337; -.
DR   eggNOG; COG1940; Bacteria.
DR   HOGENOM; CLU_036604_13_2_11; -.
DR   OrthoDB; 9810372at2; -.
DR   Proteomes; UP000017746; Chromosome.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01125; ROK; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017746}.
SQ   SEQUENCE   370 AA;  37456 MW;  46536A1A16B5FCBA CRC64;
     MTTRATELLR VVHARPGVTR ADAARLIGVG TGATTELVGR LGQAELLAEG PTAPSGARGR
     PTTALIPHPR GPLIAAASIT HEAWRVDVVE LGGSILATAG EELAGRSGDE VVAALGAAVH
     RLRIEYRDRI RGIGISVPGT VSRDLMLDAS QLGWQDVDLA VAWPRAEIFV AGNDATLAAS
     AESRRGIAVG AAVALHLRIE AGLGGAVVDG GRVLIGALGA SGEFGHMPFG DPAVRCPCGA
     FGCWGTAVDG SALARLLGHE TPPDPVTYAR RIITDPNPEP AAAAATVATA LGRGIAGLVN
     GLDADLVTLG GLGVDLLAAA PAQLLAAYEA GLMSFRRATP PPVLPALLGD NGPIVGAAEE
     AWTALLARLT
//