ID   U5WDW5_9ACTN            Unreviewed;       291 AA.
AC   U5WDW5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   SubName: Full=Putative LysR-family transcriptional regulator {ECO:0000313|EMBL:AGZ46106.1};
GN   ORFNames=AFR_39260 {ECO:0000313|EMBL:AGZ46106.1};
OS   Actinoplanes friuliensis DSM 7358.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ46106.1, ECO:0000313|Proteomes:UP000017746};
RN   [1] {ECO:0000313|EMBL:AGZ46106.1, ECO:0000313|Proteomes:UP000017746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ46106.1,
RC   ECO:0000313|Proteomes:UP000017746};
RX   PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA   Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA   Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT   "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT   HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL   J. Biotechnol. 178:41-42(2014).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
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DR   EMBL; CP006272; AGZ46106.1; -; Genomic_DNA.
DR   RefSeq; WP_023562440.1; NC_022657.1.
DR   AlphaFoldDB; U5WDW5; -.
DR   STRING; 1246995.AFR_39260; -.
DR   KEGG; afs:AFR_39260; -.
DR   PATRIC; fig|1246995.3.peg.7945; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_4_11; -.
DR   OrthoDB; 3176554at2; -.
DR   Proteomes; UP000017746; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017746}.
FT   DOMAIN          1..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   291 AA;  31783 MW;  F369E33F0796A43E CRC64;
     MDVQLRQLRT LVAVVDAGTF TDAAAVLGVS QAAVSRSVAA LEEALGARLL QRTTRHVALT
     PTGTRIVAQA RRILEEVAHL RGIVDDSRTE LRVGYAWAAL GRHTRRVQKM WAAAHPRVPL
     VFVQSNDLTA GLSDGTADLA VIRRPLDDTR FATTEIGRES RYAAVATGST LARRRSLKVE
     DLARFTVAID SRTGTTTTDL WPADNRPAVV RETATVDEWL TLIAAGQAVG VTPEATAHQY
     PRPGVAYRVL RHAPPIVVRL AWWRDDPPAH LGELRDLARR AYDWSGTGEG L
//