ID U5WIR5_MYCKA Unreviewed; 428 AA.
AC U5WIR5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:AGZ48862.1};
GN ORFNames=MKAN_00065 {ECO:0000313|EMBL:AGZ48862.1};
OS Mycobacterium kansasii ATCC 12478.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ48862.1, ECO:0000313|Proteomes:UP000017786};
RN [1] {ECO:0000313|EMBL:AGZ48862.1, ECO:0000313|Proteomes:UP000017786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ48862.1,
RC ECO:0000313|Proteomes:UP000017786};
RG McGill University Mycobacterium genome consortium;
RA Veyrier F.J., Behr M.A.;
RT "Genome sequence of Mycobacterium kansasii.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; L-ascorbate biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005147}.
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DR EMBL; CP006835; AGZ48862.1; -; Genomic_DNA.
DR RefSeq; WP_023363938.1; NC_022663.1.
DR AlphaFoldDB; U5WIR5; -.
DR SMR; U5WIR5; -.
DR GeneID; 29699789; -.
DR KEGG; mkn:MKAN_00065; -.
DR eggNOG; COG0277; Bacteria.
DR HOGENOM; CLU_003896_4_3_11; -.
DR OrthoDB; 9800184at2; -.
DR UniPathway; UPA00132; -.
DR Proteomes; UP000017786; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0003885; F:D-arabinono-1,4-lactone oxidase activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2520; -; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR007173; ALO_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR010031; FAD_lactone_oxidase-like.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR006093; Oxy_OxRdtase_FAD_BS.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR NCBIfam; TIGR01679; bact_FAD_ox; 1.
DR PANTHER; PTHR43762; L-GULONOLACTONE OXIDASE; 1.
DR PANTHER; PTHR43762:SF1; L-GULONOLACTONE OXIDASE; 1.
DR Pfam; PF04030; ALO; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR PIRSF; PIRSF000136; LGO_GLO; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
DR PROSITE; PS00862; OX2_COVAL_FAD; 1.
PE 4: Predicted;
KW Ascorbate biosynthesis {ECO:0000256|ARBA:ARBA00022644};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 12..179
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 428 AA; 47741 MW; 18C3D17F43DBD9A7 CRC64;
MSTVWRNWAG EQLCAPSQIV RPTSEAELAE VVVKAAQRGE RVRAVGTGHS FTDCACTDGV
MVDMAGMQRV IDVDVATGLA TVQGGARLHP LFAQLAERGL GLENQGDIDK QSITGATATA
THGTGARFTN VSAQVVSLRL VTAGGDILTL SEGDDYLAAR VSIGALGVIS QVTLRVVPLF
TLHRDDELRP LADTLERLDE QVDGNDHFEF FVFPYGDTAL TRTTRRSDEK PRPLPVWKRR
INDYAENAAL SLICRTGRQF PSAAPALNRL MTNLMSPATV QDHGWKVYAS ARNVKFTEME
YAIPREHARE GVQRVIDLVR RRNLPIMFPL EVRFGAPDDA FLSTAHDRDT CYIAVHQYTG
MEFETYFRAV EEIMDEYAGR PHWGKRHYQS AGTLRDRYPA WDSFAAVRDR LDPDRVFLND
YTRRVLGP
//
