ID U5WNJ1_MYCKA Unreviewed; 486 AA.
AC U5WNJ1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Fatty acid--CoA ligase {ECO:0000313|EMBL:AGZ50522.1};
GN ORFNames=MKAN_09685 {ECO:0000313|EMBL:AGZ50522.1};
OS Mycobacterium kansasii ATCC 12478.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ50522.1, ECO:0000313|Proteomes:UP000017786};
RN [1] {ECO:0000313|EMBL:AGZ50522.1, ECO:0000313|Proteomes:UP000017786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ50522.1,
RC ECO:0000313|Proteomes:UP000017786};
RG McGill University Mycobacterium genome consortium;
RA Veyrier F.J., Behr M.A.;
RT "Genome sequence of Mycobacterium kansasii.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP006835; AGZ50522.1; -; Genomic_DNA.
DR RefSeq; WP_023367558.1; NC_022663.1.
DR AlphaFoldDB; U5WNJ1; -.
DR GeneID; 29697159; -.
DR KEGG; mkn:MKAN_09685; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_7_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000017786; Chromosome.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AGZ50522.1}.
FT DOMAIN 25..355
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 406..479
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 486 AA; 52208 MW; 80C33AF187CB8327 CRC64;
MTQSARQRRD EPPWETIPEM VLSAGERFGD AEAVVDGPLR LTFAELAERV RRAAGAFAAA
GVNNGDRVAI WAPNSAEWII AAFGLLTAGG VLVPVNTRFK TAEAADIIGR SGAKAVLVEK
GFLGMDFTAP AGIPVVDVKS GFLDSGKPFE RAVSGSDVAD IIYTSGTTGR PKGVMMDHAQ
TLRHYAEWCD RADLRQGDRY LIVNPFFHIF GYKAGCIASL IRGATIVPVP IFELENVLKL
IEQEHITMLP GPPTLYHSLL GAQGGRDLSS LRAGVTGAAD IPVELVRRVR TELPFQTLMT
GYGLTEAGTV TLSRPEDSFE DIATTAGVAC DGIEVDIAAD GEILVRGYNV MKGYLDDPVA
TAEAIDDQGW LHTGDLGSLD EAGRLRVVGR KKDMFIVGGF NAYPAEIEGF LLEHEAVAQA
AVIGVRDDRL GQVGKAFVVR KGAVSADELI SWCRERMAGF KVPRSVQFVE ALPLNATGKV
VKDQLR
//
