ID U5WS97_MYCKA Unreviewed; 310 AA.
AC U5WS97;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=rRNA methyltransferase {ECO:0000313|EMBL:AGZ50945.1};
GN ORFNames=MKAN_12240 {ECO:0000313|EMBL:AGZ50945.1};
OS Mycobacterium kansasii ATCC 12478.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ50945.1, ECO:0000313|Proteomes:UP000017786};
RN [1] {ECO:0000313|EMBL:AGZ50945.1, ECO:0000313|Proteomes:UP000017786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ50945.1,
RC ECO:0000313|Proteomes:UP000017786};
RG McGill University Mycobacterium genome consortium;
RA Veyrier F.J., Behr M.A.;
RT "Genome sequence of Mycobacterium kansasii.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family.
CC {ECO:0000256|ARBA:ARBA00007228}.
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DR EMBL; CP006835; AGZ50945.1; -; Genomic_DNA.
DR RefSeq; WP_023368490.1; NC_022663.1.
DR AlphaFoldDB; U5WS97; -.
DR GeneID; 29701869; -.
DR KEGG; mkn:MKAN_12240; -.
DR eggNOG; COG0566; Bacteria.
DR HOGENOM; CLU_021322_0_0_11; -.
DR OrthoDB; 9785673at2; -.
DR Proteomes; UP000017786; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AGZ50945.1};
KW Transferase {ECO:0000313|EMBL:AGZ50945.1}.
FT DOMAIN 70..146
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 310 AA; 32463 MW; E08540070C8DEE5A CRC64;
MAGNSQRRGA VRKSGTKKGA PVGSGGQRRR GLEGRGPTPP AHMRPNHPAA KRAKAAPRRP
VRSRIDEAET VLGRNPVLEC LRAGVPATAL YVALGAEADE RVTESVARAA DSGISILEVP
RADLDRMTAN HLHQGIALQV PPYHYAHPDD LLAAAMDTPP ALLVALDNIS DPRNLGAIVR
SVAAFGGHGV LIPQRRSASV TAVAWRTSAG AAARIPVARA TNLTRTLKDW ADRGLRVIGL
DAAGETAVDD LDGSDPLVVV VGSEGKGLSR LVRQNCDEVV SIPMAGRAES LNASVAAGVV
LAEIARQRRT
//
