ID   U6CVG7_NEOVI            Unreviewed;       570 AA.
AC   U6CVG7;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Vacuolar protein sorting 45 homolog {ECO:0000313|Ensembl:ENSNVIP00000003732.1};
DE   SubName: Full=Vacuolar protein sorting-associated protein 45 {ECO:0000313|EMBL:CCP74426.1};
GN   Name=VPS45 {ECO:0000313|EMBL:CCP74426.1};
OS   Neovison vison (American mink) (Mustela vison).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Neogale.
OX   NCBI_TaxID=452646 {ECO:0000313|EMBL:CCP74426.1};
RN   [1] {ECO:0000313|EMBL:CCP74426.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Pool of brain {ECO:0000313|EMBL:CCP74426.1};
RA   Anistoroaei R., Christensen K.;
RT   "An American mink transcriptome.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNVIP00000003732.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC       {ECO:0000256|ARBA:ARBA00009884}.
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DR   EMBL; HAAF01002600; CCP74426.1; -; mRNA.
DR   Ensembl; ENSNVIT00000004379.1; ENSNVIP00000003732.1; ENSNVIG00000002966.1.
DR   GeneTree; ENSGT00550000075028; -.
DR   OrthoDB; 49088at2759; -.
DR   Proteomes; UP000694425; Unplaced.
DR   GO; GO:0010008; C:endosome membrane; IEA:Ensembl.
DR   GO; GO:0000139; C:Golgi membrane; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.40.60; -; 1.
DR   Gene3D; 3.40.50.1910; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR027482; Sec1-like_dom2.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   PANTHER; PTHR11679:SF3; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45; 1.
DR   PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR   Pfam; PF00995; Sec1; 1.
DR   PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR   SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694425};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
SQ   SEQUENCE   570 AA;  64963 MW;  8FFC7E43D7CAA367 CRC64;
     MNVVFAVKQY VSKMIEDSGP GMKVLLMDKE TTGIVSMVYT QSEILQKEVY LFERIDSQNR
     EVMKHLKAIC FLRPTKENVG YLIQELRRPK YSIYFIYFSN VISKSDVKSL AEADEQEVVA
     EVQEFYGDYI AVNPHLFSLN ILGCCQGRNW DPAQLSRTTQ GLTALLLSLK KCPMIRYQLS
     SEAAKRLAEC VKQVITKEYE LFEFRRTEVP PLLLILDRCD DAITPLLNQW TYQAMVHELL
     GINNNRIDLS RVPGISKDLR EVVLSAENDE FYANNMYLNF AEIGSNIKNL MEDFQKKKPK
     EQQKLESIAD MKAFVENYPQ FKKMSGTVSK HVTVVGELSR LVSERNLLEV SEVEQELACQ
     NDHSSALQNV KRLLQNPKVT EFDAARLVML YALHYERHSS NSLPGLMMDL RNKGVSEKYR
     KLVSAVVEYG GKRVRGSDLF SPKDAVAITK QFLKGLKGVE NVYTQHQPFL HETLDHLIKG
     KLKENVYPYL GPSTLRDRPQ DIIVFIIGGA TYEEALTVYN LNRTTPGVRI VLGGTTVHNT
     KSFLEEVLAS GLHSRSRESS QVTSRSASRR
//