ID   U6D239_NEOVI            Unreviewed;       128 AA.
AC   U6D239;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Glutamate NMDA receptor subunit epsilon-4 {ECO:0000313|EMBL:CCP76716.1};
DE   Flags: Fragment;
GN   Name=NMDE4 {ECO:0000313|EMBL:CCP76716.1};
OS   Neovison vison (American mink) (Mustela vison).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Neogale.
OX   NCBI_TaxID=452646 {ECO:0000313|EMBL:CCP76716.1};
RN   [1] {ECO:0000313|EMBL:CCP76716.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Pool of brain {ECO:0000313|EMBL:CCP76716.1};
RA   Anistoroaei R., Christensen K.;
RT   "An American mink transcriptome.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; HAAF01004891; CCP76716.1; -; mRNA.
DR   AlphaFoldDB; U6D239; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR   InterPro; IPR001508; Iono_Glu_rcpt_met.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966:SF385; GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2D; 1.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   PRINTS; PR00177; NMDARECEPTOR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023286};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:CCP76716.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        45..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          44..128
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00060"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CCP76716.1"
FT   NON_TER         128
FT                   /evidence="ECO:0000313|EMBL:CCP76716.1"
SQ   SEQUENCE   128 AA;  14090 MW;  9C15583A84B5ECF9 CRC64;
     LTINEERSEI VDFSVPFVET GISVMVARSN GTVSPSAFLE PYSPAVWVMM FVMCLTVVAV
     TVFIFEYLSP VGYNRSLATG KRPGGSTFTI GKSIWLLWAL VFNNSVPVEN PRGTTSKIMV
     LVWAFFAV
//