ID   U6DS45_NEOVI            Unreviewed;       447 AA.
AC   U6DS45;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Angiopoietin-2 {ECO:0000256|ARBA:ARBA00015280};
DE   Flags: Fragment;
GN   Name=ANGP2 {ECO:0000313|EMBL:CCP85805.1};
OS   Neovison vison (American mink) (Mustela vison).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Neogale.
OX   NCBI_TaxID=452646 {ECO:0000313|EMBL:CCP85805.1};
RN   [1] {ECO:0000313|EMBL:CCP85805.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Pool of brain {ECO:0000313|EMBL:CCP85805.1};
RA   Anistoroaei R., Christensen K.;
RT   "An American mink transcriptome.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; HAAF01013983; CCP85805.1; -; mRNA.
DR   AlphaFoldDB; U6DS45; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   CDD; cd00087; FReD; 1.
DR   Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR   InterPro; IPR036056; Fibrinogen-like_C.
DR   InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR   InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR   NCBIfam; NF040941; GGGWT_bact; 1.
DR   PANTHER; PTHR19143:SF199; ANGIOPOIETIN-2; 1.
DR   PANTHER; PTHR19143; FIBRINOGEN/TENASCIN/ANGIOPOEITIN; 1.
DR   Pfam; PF00147; Fibrinogen_C; 1.
DR   SMART; SM00186; FBG; 1.
DR   SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR   PROSITE; PS51406; FIBRINOGEN_C_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..447
FT                   /note="Angiopoietin-2"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004668364"
FT   DOMAIN          274..447
FT                   /note="Fibrinogen C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51406"
FT   COILED          166..246
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         447
FT                   /evidence="ECO:0000313|EMBL:CCP85805.1"
SQ   SEQUENCE   447 AA;  51304 MW;  FD089CACAEE238CF CRC64;
     MWQIVFFTLG CDLVLAAAYN NFRRSMDSIG RRQYQVQHGA CSYTFLLPET DNCRPSSSYV
     PNAVQRDAPL DYDDSVQRLQ VLENIMENNT QWLMKLENYI QDNMKREMVE MQQNAVQNQT
     AVMIEIGTNL LNQTAAQTRK LTDVEAQVLN QTTRLELQLL EHSLSTNKLE KQILDQTSEI
     NKLQDKNSFL EKKVLDMEDK HIVQLRSIKE EKDQLQVLVS KQNSIIEELE KQLVTATVNN
     SVLQKQQHDL METVHNLLSM ISTSNSAKNS FDVKEEQVIF RDCAEVFKSG LTANGIYTLT
     FPNSTEEIKA YCDMETSGGG WTVIQRREDG SVDFQKTWKE YKVGFGNPSG EHWLGNEFVF
     QVTNQQPYVL KIHLKDWEGN EAYSLYEHFY LSGEELNYRI HLKGLTGTAG KISSISQPGN
     DFSTKDADND KCICKCAQML TGGWWFD
//