ID U6GFG3_EIMAC Unreviewed; 1002 AA.
AC U6GFG3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=DNA replication licensing factor, putative {ECO:0000313|EMBL:CDI77314.1};
GN ORFNames=EAH_00023230 {ECO:0000313|EMBL:CDI77314.1};
OS Eimeria acervulina (Coccidian parasite).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=5801 {ECO:0000313|EMBL:CDI77314.1};
RN [1] {ECO:0000313|EMBL:CDI77314.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI77314.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDI77314.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI77314.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|RuleBase:RU004070}.
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DR EMBL; HG670622; CDI77314.1; -; Genomic_DNA.
DR RefSeq; XP_013252306.1; XM_013396852.1.
DR AlphaFoldDB; U6GFG3; -.
DR EnsemblProtists; CDI77314; CDI77314; EAH_00023230.
DR GeneID; 25270393; -.
DR VEuPathDB; ToxoDB:EAH_00023230; -.
DR OMA; HRNEMLY; -.
DR OrthoDB; 147095at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF46; DNA REPLICATION LICENSING FACTOR MCM3; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|RuleBase:RU004070};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070}.
FT DOMAIN 424..639
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..697
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1002 AA; 107908 MW; 6B17125A5440214D CRC64;
MASYIDDEID GSLGGGHTEG NMMGATSIDM TQAAAPRRAA AAAAAAAATG TATEAEPDWK
ADAIVEQQMG HDGNREKTAT VKALTEAFQQ TLAAIPGLSQ QLDVLQQAAA AVCLGMPAEG
KGLRVSSSSS SGRSNSSLQQ RLILSISDVV SVSSFSFYNH PLIKNPCAAL PALEYAVAEE
WKNRGALGPA PRVGVGGWLG ASHLTPRGLK STHLNCLVAL EGVVNRCAAP HPRIHRAVYL
TEDALQHQQQ LLHLQHQQPQ QQQQQQQQQT PIITPQEREI HLRSFYDVSD LDKDIRDAQP
PPQKDPEGRR INRQEIGYCQ YQNHQKFFVQ EAPETAPTGQ LPRWVEVLAA ADLCESVKCG
DRVRIFGVYR PRASAANNQT TGYVKPLLVA NNIEVLNAAA RASMLQSLPA DLMNIKTFAS
RRDLLEVMAR SVAPAVCGHD LVKRGLLLQL CGGSSLGSSS SNNSSSSSIG HRVRGDIHVL
LLGDPSAGKS QLLRFVLRLL PGAISTTGRG SSGVGLTAAV ATDGDTMERR VEAGAMVMAD
KNIVCIDEFD KMQQGDRAAI HEVMEQQTVS VAKAGIHTTL NARCSVLAAA NPLYGCWSPD
LPFSSQVAFE DSLLSRFDLI FILRDSTSCE EDERLAEAVL RNVSEKAKPA AATTTTAAAA
ATAAGGDKRL QGDSFIQPQS DMHKPSHAAT ADLQQQEAEP TKAFYHRNEM LYYDKQGREH
ECLTHEFLRK YIELVRCGGL AAVEDGDLPQ QQQQQEGPRL SESAAAALAD FYTTIRQRAV
QQREEGAAAT NNLLQPVTED VQVAQQLLLH TLFGEDTFRD EETETETETD EEEEAAPARR
RKPRRKAADS QHKSCPCAAV RRAAVAAAFA AAFAAADEAM AQEMEGLEIG ETKKRRTRRA
AAAAAGGGDA AAEARERNEA LQSLHAQGLS SDIVQSLILH CIKELDQGSG VSEAALLEAV
SARALSRGLL QPSAEEFQKS LHDLNSKDSA PILVHDGLVY EC
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