ID U6GJE9_EIMAC Unreviewed; 268 AA.
AC U6GJE9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=NADP-dependent oxidoreductase domain-containing protein {ECO:0000259|Pfam:PF00248};
GN ORFNames=EAH_00014400 {ECO:0000313|EMBL:CDI80285.1};
OS Eimeria acervulina (Coccidian parasite).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=5801 {ECO:0000313|EMBL:CDI80285.1};
RN [1] {ECO:0000313|EMBL:CDI80285.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI80285.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDI80285.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI80285.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG671173; CDI80285.1; -; Genomic_DNA.
DR RefSeq; XP_013249742.1; XM_013394288.1.
DR AlphaFoldDB; U6GJE9; -.
DR EnsemblProtists; CDI80285; CDI80285; EAH_00014400.
DR GeneID; 25269510; -.
DR VEuPathDB; ToxoDB:EAH_00014400; -.
DR OMA; PGRHHGY; -.
DR OrthoDB; 5305445at2759; -.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0044281; P:small molecule metabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 2.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR018170; Aldo/ket_reductase_CS.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43827; 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE; 1.
DR PANTHER; PTHR43827:SF15; ALDO_KET_RED DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PIRSF; PIRSF000097; AKR; 2.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
PE 4: Predicted;
FT DOMAIN 92..236
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
FT ACT_SITE 62
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-1"
SQ SEQUENCE 268 AA; 30668 MW; EF18633746769D5B CRC64;
MSCPSLAGVD LLAAAKCRTL YNGVKLPMIG LGTWRLRGDR LRSGVFGALN ERYGLIDSAA
VYENEEEIRE LLKEAGSGGV DANSHENRQR RIESWRALEQ LYEEKKVRAI GVSNFLVPHL
EQLMEDGAKI RPMVDQIEWH PMCWVPDLIP YAEKHNITLQ AYSSLGSGEN RLMEHEVVKQ
IAKEINKSPS VVLLRWPLQQ GLVVIPCSTS QEHLRENLEA LDVELSEDQM KRLANCRIVE
FMQAYLPVVF SAITRPEEWW LHLKWFGY
//
