ID   U6KL22_EIMTE            Unreviewed;       824 AA.
AC   U6KL22;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Cullin family protein, putative {ECO:0000313|EMBL:CDJ36952.1};
GN   ORFNames=ETH_00004725 {ECO:0000313|EMBL:CDJ36952.1};
OS   Eimeria tenella (Coccidian parasite).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=5802 {ECO:0000313|EMBL:CDJ36952.1};
RN   [1] {ECO:0000313|EMBL:CDJ36952.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ36952.1};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDJ36952.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ36952.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; HG673746; CDJ36952.1; -; Genomic_DNA.
DR   RefSeq; XP_013227790.1; XM_013372336.1.
DR   AlphaFoldDB; U6KL22; -.
DR   EnsemblProtists; CDJ36952; CDJ36952; ETH_00004725.
DR   GeneID; 25250153; -.
DR   VEuPathDB; ToxoDB:ETH2_0818700; -.
DR   VEuPathDB; ToxoDB:ETH_00004725; -.
DR   OMA; IREWDRY; -.
DR   OrthoDB; 21270at2759; -.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
FT   DOMAIN          435..708
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          339..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          544..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        545..564
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   824 AA;  94177 MW;  C5024535C81A089B CRC64;
     MDGHGELVTL EEGWTKLRLQ GIEKVQRFLE QRPERGHASK RVCVVSNEDY AAIYTMVYTM
     CTQRSPYNFS QDLYQLYGDS IVRYVHSTVL PSLENRRGSD LLEELLCRWE NHRTLVKWLQ
     KFFAYLDRYY VKMYMEAPLV KRGIAIFKDH VFERVKQPVS AAIEDAIRRQ REGESLDEES
     VAQLVCMYIG LDPEDEGLGL YQRELEDLLL ASTKQFYDRK AREWIASSTF SEYLLLAEAA
     LEAEARRCER YLHSSSSSKL LGVVVKSTLQ QHQQELLEKD TAIPFLLAGE GRAELRMAHR
     LFALVDGAVE DLAKQFKVYI SACGDKLVQQ RVAAMKETQQ MRAQGSASSS SNAALTQQQQ
     RQQDIIAEHR FVESVLDLHD RFKSITLDCF RAQQRIAHDA LGSSARPTPQ ADSLFQKALK
     EAFESFVNAQ SLQPPFAQLL ASFCDRILRK AGGERMGDDE IEECLMKVVE IFNYVTDKDL
     FAEQYRTQLG RRLLHETSAS LELERLLIAK LRLKCGAHFT AKVEGMVNDL QVAAGLMRSF
     QQQQQEEQLK RKTDEQESKV NESASRIKES VSSATVETVM IGDVEFSVQA LSTAHWPTYP
     APDLRLPPQL AQCVNAFEQF YTSQTQHRKL TWVNSLGTAL VAAQLQNRQD LICNTMQAAL
     LLRFNRKQDD GCGRTICCAG DPALSVQQLV EELRLDELTV KKLLGSLMLG RFKILKKTES
     DLFQVNESFS CLHRKIKLPT PVQEEAQCRA RVEEDRSITV DAAIVRIMKT RKSLSHQQLV
     GEVMAQLHFF QPPPKLLKER IQDLIAREFL ERDKDKPTQY NYVA
//