ID U6KS27_EIMTE Unreviewed; 1627 AA.
AC U6KS27;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 03-MAY-2023, entry version 31.
DE SubName: Full=Splicing factor Prp8, related {ECO:0000313|EMBL:CDJ40776.1};
DE Flags: Fragment;
GN ORFNames=ETH_00015540 {ECO:0000313|EMBL:CDJ40776.1};
OS Eimeria tenella (Coccidian parasite).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=5802 {ECO:0000313|EMBL:CDJ40776.1};
RN [1] {ECO:0000313|EMBL:CDJ40776.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ40776.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ40776.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ40776.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG675259; CDJ40776.1; -; Genomic_DNA.
DR RefSeq; XP_013231526.1; XM_013376072.1.
DR EnsemblProtists; CDJ40776; CDJ40776; ETH_00015540.
DR GeneID; 25252262; -.
DR VEuPathDB; ToxoDB:ETH2_1260500; -.
DR VEuPathDB; ToxoDB:ETH_00015540; -.
DR OMA; ANKWNTS; -.
DR OrthoDB; 246127at2759; -.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0030623; F:U5 snRNA binding; IEA:InterPro.
DR GO; GO:0017070; F:U6 snRNA binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR Gene3D; 3.30.43.40; Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain; 1.
DR InterPro; IPR012591; PRO8NT.
DR InterPro; IPR012592; PROCN.
DR InterPro; IPR027652; PRP8.
DR InterPro; IPR019581; Prp8_U5-snRNA-bd.
DR InterPro; IPR042516; Prp8_U5-snRNA-bd_sf.
DR InterPro; IPR019580; Prp8_U6-snRNA-bd.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR019582; RRM_spliceosomal_PrP8.
DR PANTHER; PTHR11140; PRE-MRNA SPLICING FACTOR PRP8; 1.
DR PANTHER; PTHR11140:SF0; PRE-MRNA-PROCESSING-SPLICING FACTOR 8; 1.
DR Pfam; PF08082; PRO8NT; 1.
DR Pfam; PF08083; PROCN; 1.
DR Pfam; PF10598; RRM_4; 1.
DR Pfam; PF10597; U5_2-snRNA_bdg; 1.
DR Pfam; PF10596; U6-snRNA_bdg; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
FT DOMAIN 88..238
FT /note="PRO8NT"
FT /evidence="ECO:0000259|Pfam:PF08082"
FT DOMAIN 428..833
FT /note="PROCN"
FT /evidence="ECO:0000259|Pfam:PF08083"
FT DOMAIN 1018..1108
FT /note="RNA recognition motif spliceosomal PrP8"
FT /evidence="ECO:0000259|Pfam:PF10598"
FT DOMAIN 1242..1375
FT /note="Pre-mRNA-processing-splicing factor 8 U5-snRNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF10597"
FT DOMAIN 1474..1627
FT /note="Pre-mRNA-processing-splicing factor 8 U6-snRNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF10596"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1627
FT /evidence="ECO:0000313|EMBL:CDJ40776.1"
SQ SEQUENCE 1627 AA; 190433 MW; 4741DA165EB59C42 CRC64;
MAQKEDNSAQ QQPAPRQQPQ QQQQQQQQQA GGAYGKASQG GAAAGAAAQR AKAKTQEELL
QEKARKWQQL TTKRYSWRQQ VGCTYTEKEP MPPEHLRKLV KDHGDMSSRK FRQDRRVYLG
ALKFLPHAVF KLLENMPMPW EQARNVAVLY HATGAITFVA ETPFVIEPVY LAQWGSCWIL
MRREKRDRRH FKRMRFPPFD DEEPPLDYGE NVLAVEPLEA IRMELDEEED AAVAEWLYCS
KPLQQQQQHV PGPSYRRWRL EVQQLAVLQR LAHQLLSDLQ DLNYFYLFNL EAFCTAKALN
LAIPGGPKFE PLFRDSQEEE EDWNEFNDVS KIIIRQQIRT EYRVAFPHLY NNRPRSVALP
PYHSPAVSFV KPEDPELPAF YFDPIINPLP AYKTNKDFDA LADPSVVEGF ELPRCVRAFL
EESPLCTDTT AAGISLYWAC RPFNLRAGRM RRAQDVPLVQ TWFREHAPQN YPVKVRVSYQ
KLLKCWVLCH LHSRPPKSLK KRNLFRVFKT TKFFQVTEID WVEAGLQVAR QGYNMLNLLI
HRKNLNYLHL DYNFNLKPVK TLTTKERKKS RFGNAFHLCR EILRLTKLTV DSHVQFRLGN
VDAFQLADGL QYIFAHVGQL TGMYRYKYRL MRQVRMCKDL KHLIYYRFNT GPVGKGPGCG
FWAPGWRVWL FFLRGVLPLL ERWLGNLLAR QFEGRVSKGT AKTVTKQRVE SHFDLELRAA
VMHDILDLMP EGVKASKART ILQHLSEAWR CWKANIPWKV PGLPAPIENM ILRYVKMKAD
WWTNAAYYNR ERIRRGATVD KTVCRKNLGR LTRLWLKAEQ ERQHAYLKDG PYLSGEEAVA
IYTTAVHWLE SRRFTHIPFP PLNYKHDTKL LVLALERLKE FYSVKSRLNQ SQREELGLIE
QAYDNPHEAL SRIKRHLLTQ RAFKELRLEF MDLYSHLVPI YEIDPLEKIT DAYLDQYLWY
EGDSRHLFPS WVKPADAEPP PLLVFKFCQG INNLTDVWNT ADGETLVLLE SKFEKVYEKV
DLTLLNRLLR LIVDHNIADY ITAKNNVGVS FKDMSHVNSF GLIRGLQFSS FVFQYYALVL
DLLLLGLTRA TEIAGPPALP NEFLSFPDVQ TETRHPIRLY CRYIDRFWVV FKFTKEESRD
LVQRYLTENP DPNNENVVGY PNKTCWPRDC RMRRMKRDVN LGRAVFWEMA NRLPRSLATL
NWTSSFASVY SVDNPNLLFS MGGFECRILP KVRLQTEQFL QREGVWKLQN ESTKEMAAQA
FLKVGEDGMR RFENRVRMVL MSSGATTFTK IANKWNTTLI SLMTYFREAV VHTEALLDLL
VKCENKIQTR IKIGLNSKMP SRFPPVVFYT PKELGGLGML SMGHILIPQS DLRYSQQTES
GITHFRSGMS HEEDQLIPNL YRYLQTWESE FVESQRVWAE YALKRAEAAA QSRRLTLEDL
EDSWDRGIPR INTLFQKDRH TLAYDKGWRV REDFRQFQQL KAHPFWWTHQ RHDGKLWNLN
NYRTDMIQAL GGVEGILEHT LFKGTYFPTW EGLFWEKASG FEESMKYKKL TNAQRSGLNQ
IPNRRFTLWW SPTINRANVY VGFQVQLDLT GIFMHGKIPT LKISLIQIFR AHLWQKVHES
IVMDLCQ
//
