ID   U6MIM0_9EIME            Unreviewed;      1376 AA.
AC   U6MIM0;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Histone deactylase, putative {ECO:0000313|EMBL:CDJ62309.1};
GN   ORFNames=ENH_00012590 {ECO:0000313|EMBL:CDJ62309.1};
OS   Eimeria necatrix.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ62309.1};
RN   [1] {ECO:0000313|EMBL:CDJ62309.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ62309.1};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDJ62309.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ62309.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HG722429; CDJ62309.1; -; Genomic_DNA.
DR   RefSeq; XP_013439671.1; XM_013584217.1.
DR   GeneID; 25471444; -.
DR   VEuPathDB; ToxoDB:ENH_00012590; -.
DR   OrthoDB; 69755at2759; -.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00850; Hist_deacetyl; 2.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT   REPEAT          264..296
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          542..748
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
FT   DOMAIN          822..1009
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
FT   REGION          766..801
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1077..1169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1321..1347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1331..1345
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1376 AA;  144611 MW;  372D701502C8B172 CRC64;
     MRPEADPACP PVALGMADCA VFVSPQGGVS LARSTSSGSA PTGPHQPLLH LTGDVSCYRE
     GTLHRLIAAR NIPGVRQWLS NPFCRDTIND FNHAGETPLH VALHVCEPRI LSLLLNPPPV
     QMPPQCLLAC SSSSSGGGGE CVGVAPSGEG TSAHGEWATD AANAAAAAAA ATVDFSLPLD
     DIPALHILVG RSSFAHVRAD AAECLRRLLH HVGLLHMTTG GSRVCSRCTF TATSSRGRSI
     SSGNCPPRVE CGLQELDLDA TDGSGKTALH VAAAGGGAAA VELLLHAGAD PLIADKRGLL
     PLHVAVDSRS VGCLLLLLAH TFPEDCFYWC DKLEQQQQDR LVVGSAAEAA SVGGCPDARA
     PKKVVLQRAE RRPLVHCATS SSLVYRIARR CVRRCSFRCL AALLSYPLVA ACSNRSEPSA
     EAPESVMALQ LLHAQQLQEL VSLARRSGCL QLFLSTLSEL VDAEPSHSVA EAVIAEATGG
     RGPLQGPIAY VQQRCSRSGR CYRVPEAAGT LLATHESCMH HLPLPEPSDF PVKRFKLMQR
     FPENPSRLEV LVHPSSGVLK AAEFRHLDWI DNAAPASLAD ILRVHDVSYI FKLKQKIRST
     FGTRSVNKSF SGSSSSSSYG GPSPVDQFAY SFADGDTPVT ALSWEAATSA AGTVIAAVDA
     VCTGAKVNAF CAVRPPGHHL GSWGAAQTAP YALTDEDIAA GSQGFCVLNN VAIGAAYARY
     NYAHKGIRRI AIVDFDAHHG NGTEQIMRNV GLKFRKLQGL SALLADGSSP AAGQRTHREA
     PWGPPSDSWE AEGARAPPED GAALQDVPVQ LPMWLGWRDE NDSEELFFAS IHAFDGNFYP
     GTGADCEDFG GPTILNVTMP VHGACSTPVE GSEGDPCCRC ERCSEQSCIG PKPRGAHLGT
     AAADATCASG DEGGYRCHYC RRPGLSPRSI RSRLLFKHRV LSRLEAFRPD LIFLSAGFDG
     HIKDPIGGEA VGWTEDDFHW LTMQVQRVAH RHCRGRCISV LEGGYNVRGG SISPLALCVR
     EHVRALVKAA HMQQEIDAHM QAQQAHAAAA EAHSQVHAKT VAGVHQEARR LAAGGLQSVA
     GSTGEEPHQE GRVTPTPHPE GSDQLDQEGP WAEPDLSDYG SDSGFSSSED ETDAFLEECE
     APDRESAVTE EEAGESGPPA APVAPGNPYV ATSSQPPFCA GVTSQGHTVQ PAAVPFIASF
     EDVPQHSFGP TVGAATTYVH PPVPGDPCCK EHVVRTVLQP TVAAAAAGAG QWVGHEDQRV
     FHTIQEGITS PSAISSLSDD TAAACSGPDA ATGTAAAAQP AGGFLVGAPC LTGSVVPAAA
     TGPPPLPHQQ PSTVLATSTS ASDAEASPRV EEHVAAEVGE PYSKAQRLQF LCGFPG
//