ID U6MQG8_9EIME Unreviewed; 243 AA.
AC U6MQG8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=5-aminolevulinate synthase, related {ECO:0000313|EMBL:CDJ66457.1};
DE EC=2.3.1.37 {ECO:0000313|EMBL:CDJ66457.1};
DE Flags: Fragment;
GN ORFNames=ENH_00020870 {ECO:0000313|EMBL:CDJ66457.1};
OS Eimeria necatrix.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ66457.1};
RN [1] {ECO:0000313|EMBL:CDJ66457.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ66457.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ66457.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ66457.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; HG723622; CDJ66457.1; -; Genomic_DNA.
DR RefSeq; XP_013434925.1; XM_013579471.1.
DR AlphaFoldDB; U6MQG8; -.
DR GeneID; 25472260; -.
DR VEuPathDB; ToxoDB:ENH_00020870; -.
DR OrthoDB; 9643at2759; -.
DR GO; GO:0003870; F:5-aminolevulinate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR13693:SF105; 5-AMINOLEVULINATE SYNTHASE; 1.
DR PANTHER; PTHR13693; CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:CDJ66457.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Transferase {ECO:0000313|EMBL:CDJ66457.1}.
FT DOMAIN 188..243
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
FT COILED 70..137
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 243
FT /evidence="ECO:0000313|EMBL:CDJ66457.1"
SQ SEQUENCE 243 AA; 26774 MW; F5E9E5EAE2040491 CRC64;
MSFAAHLQRR CPFLARHQAA ALESLLPFTL LCPVASKTLN FSVHKSHNAA AAAAAAAAAA
AAAAAEPALA AAHKQQLQHE QLQLEKKLQQ QQRQLQQLQQ QQLQLQLQQQ KLQQHKQQLQ
QQQLQQQQQQ QQQQQQQQPL PEGFYNSAAD AKLAELHTEG RYRVFAHLRR QVGAPQKALL
RGPSGDTEVT LWCSNDYLGM SQHPRVIKAA QEALASSGAG SGGTRNISGS NVYHQALEKE
IAD
//
