ID U7PL25_SPOS1 Unreviewed; 915 AA.
AC U7PL25;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Small-subunit processome Utp12 domain-containing protein {ECO:0000259|Pfam:PF04003};
GN ORFNames=HMPREF1624_08142 {ECO:0000313|EMBL:ERS95626.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS95626.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SIMILARITY: Belongs to the WD repeat PWP2 family.
CC {ECO:0000256|ARBA:ARBA00010226}.
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DR EMBL; KI440853; ERS95626.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PL25; -.
DR STRING; 1391915.U7PL25; -.
DR eggNOG; KOG0291; Eukaryota.
DR HOGENOM; CLU_010458_0_0_1; -.
DR OrthoDB; 23263at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProt.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR027145; PWP2.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR007148; SSU_processome_Utp12.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19858:SF0; PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR19858; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF04003; Utp12; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 13.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 147..188
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 191..223
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 347..388
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 389..430
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 475..516
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 753..857
FT /note="Small-subunit processome Utp12"
FT /evidence="ECO:0000259|Pfam:PF04003"
FT REGION 227..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..248
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..669
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 915 AA; 101038 MW; 3F98BCA51D0252A4 CRC64;
MKTEFKFSNL LGTVYCKGNL LYSPDGTRLY SPVGNRVTVF NLVDNTSYTL PFAHRTNIAR
LGITPRGNLL LTVDEDGQAI LTNLPRRVVL YHFSFRGPCT ALAFSPSGRF FAVGLGRKTE
VWHVPSTPDT NADGELDFAP FVRFWTYAGH FDTVQHIAWS GDSRFFLTAS KDLTTRIWNL
EREEGFSPTV LSGHRQAIVG AWFSRDQETI YTVSKDGALF EWQYLKPPRP DGEESSSDDE
ESDDDDDDDR DMRWRIAQRH YFHQNNTSLR CAAYHAASNL LVAGFSSGVF CLYEMPDFNL
IHTLSISQSD IDHVTINSSG EWLAFGASKL GQLLVWEWQS ESYILKQQGH FDAMNALVYA
PDGQRIVTTA DDGRIKVWDI ASGFCVVTFT EHTSGVTACE FARKGNVLFT ASLDGSIRAW
DLVRYRNFRT FTAPTRLSFA CMAVDPSGEV VAAGSVDSFD IHIWSVQTGQ LLDRLSGHEG
PVSTLAFAPD GSVLVSGSWD RTARIWSVFN RTQTSEPLQL QADVLDMAVR PDSQQLAIST
LDGQLTFWSI ADAAQVAGLD GRRDVSGGRT ISDRRTAANV AGTKSFGCIR YSTDGSCLLA
AGRSKYICLY SVTTGVLLKK FTVSVNLSLS GTQEFLHSGK LTEAGPAGAL DEQGELSDRE
DRLDRSLPGS KRGGDPSARR SVPDVRVSGV AFAPTGLAFC AASTEGLLVY SLDTTLPFDP
FDLSMEITPA STLQVLREEH DYLKALVMAF RLNEAALLQH VFLDVPHQNI PLVVAGVPTV
YVARLLRFVA AQTEQSPHIE FCLLWIKALV DRHGAWLTAN RGKLDVELRV VARAVGRMRD
EIRRLADENV YTVDYLLDQA KARQATKKLA AAQPTAVVPA LTQKGEKYKA AEEPHAEVVV
FDDGDDDEEG WLGMD
//
