ID U7PUI8_SPOS1 Unreviewed; 415 AA.
AC U7PUI8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=18S rRNA biogenesis protein RCL1 {ECO:0000313|EMBL:ERS98606.1};
GN ORFNames=HMPREF1624_05393 {ECO:0000313|EMBL:ERS98606.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS98606.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the RNA 3'-terminal cyclase family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00007089}.
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DR EMBL; KI440846; ERS98606.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PUI8; -.
DR STRING; 1391915.U7PUI8; -.
DR eggNOG; KOG3980; Eukaryota.
DR HOGENOM; CLU_027882_1_0_1; -.
DR OrthoDB; 231692at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd00875; RNA_Cyclase_Class_I; 1.
DR Gene3D; 3.65.10.20; RNA 3'-terminal phosphate cyclase domain; 1.
DR Gene3D; 3.30.360.20; RNA 3'-terminal phosphate cyclase, insert domain; 1.
DR InterPro; IPR013791; RNA3'-term_phos_cycl_insert.
DR InterPro; IPR023797; RNA3'_phos_cyclase_dom.
DR InterPro; IPR037136; RNA3'_phos_cyclase_dom_sf.
DR InterPro; IPR000228; RNA3'_term_phos_cyc.
DR InterPro; IPR016443; RNA3'_term_phos_cyc_type_2.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR InterPro; IPR036553; RPTC_insert.
DR NCBIfam; TIGR03400; 18S_RNA_Rcl1p; 1.
DR PANTHER; PTHR11096; RNA 3' TERMINAL PHOSPHATE CYCLASE; 1.
DR PANTHER; PTHR11096:SF1; RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN; 1.
DR Pfam; PF01137; RTC; 1.
DR Pfam; PF05189; RTC_insert; 1.
DR SUPFAM; SSF55205; EPT/RTPC-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 11..346
FT /note="RNA 3'-terminal phosphate cyclase"
FT /evidence="ECO:0000259|Pfam:PF01137"
FT DOMAIN 211..317
FT /note="RNA 3'-terminal phosphate cyclase insert"
FT /evidence="ECO:0000259|Pfam:PF05189"
SQ SEQUENCE 415 AA; 43188 MW; A75C16440FD55382 CRC64;
MAGPSGSDFV RFTGHRFLAQ RLLLATLTGR PVHISSIRSS SPTNPGLAPH EVSLLRLFDA
VTNGSAFQIS YTGTTITFHP GLITGTVAGA GATEDDVIEH NIPAGCTRGI SYFLLPMALL
APFSKAHVNI RFSGPGVITS ATDTGDISAD AFRLAILPLY GLFGIPPARI ELNIRQRSCA
GHGDRRGNGV VELRFASQVR LPKTLHLHRG AGRIKRIGGV AYSVGVSASN NKRMIHAARG
VLNALTGEIK IAEAPPSKDD GHGGGDKPGI GFGLCLVAES TVNGVVYSAD VVSPAQGGVL
AEDLGTQCAH RLLEAIAQGG CVSWTAAPTV LTLMAMGSED VGRLRVSRDV VAAEEVMGLA
RDLKAFGASS WGLRQAEDDV IGGGDSEDDE DAHSKHDVLI SIKGTGLGNV GRKVA
//
