ID U7Q1Z2_SPOS1 Unreviewed; 555 AA.
AC U7Q1Z2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=4-coumarate-CoA ligase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1624_00183 {ECO:0000313|EMBL:ERT01889.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT01889.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
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DR EMBL; KI440842; ERT01889.1; -; Genomic_DNA.
DR AlphaFoldDB; U7Q1Z2; -.
DR STRING; 1391915.U7Q1Z2; -.
DR eggNOG; KOG1176; Eukaryota.
DR HOGENOM; CLU_000022_59_2_1; -.
DR OrthoDB; 1404660at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR CDD; cd05911; Firefly_Luc_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018087}.
FT DOMAIN 32..403
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 454..534
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 555 AA; 61172 MW; D33FB69E2137F88F CRC64;
MPFESPFPPL TIPEVDLWSL LFERKSKPFS DSKEIFTDSE TGRSYTFGDL RSTSLEFGKG
LQSLWNWKRG DVLAFYTPNN IDTPPAMLGL LWAGGICSPA NPLYTEHELT FQLRDSGATA
VITQLPFLET ARRAAKAVGI PEDRIILLGD AHDPSGRFRH FSAIRNPSFK GRATAEPVDV
HKDLAFLVYS SGTTGLPKGV CLTHYNVVAN VLQMSSMDGL IFHPFGGTDG KGDKGLGITP
FFHIYGLTCC ILVFINTGWE LISMPRFDLE RACQLIEKYK ISFAYVPPPV VLAFSKHPVV
DKYDLTSMRM FHSGAAPLTP ELATALWDRL KIPVKQGYGL SETSPVAMMQ LLHEWGKFMG
SVGRLLPNMQ ARLVDPDEGT DVAELGKPGE LWLKGPNVFQ GYLNLPDNTK ATMSADGYFK
TGDIFIADKY GNFTCVDRLK ELIKYKGFQV PPAELEGILL GHKDIADAGV IGVEDKAQAT
EVPRAYVVMK PGLPTDAAKA KEIVDWLASL TAPHKKLRGG VHFVKEIPKS PSGKILRRVL
RDQVRQAEKA GASKL
//
